IpiRecord: IPI00000049

IPI00000049 - TNFSF10, UNCHARACTERIZED PROTEIN TNFSF10.
Uniprot Accession: A6NLJ6
Uniprot ID: A6NLJ6_HUMAN
Mapping: Chr 3, 173706159 - 173723963
Entrez Gene: 8743
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_2326)
Rat: Tnfsf10, TNF-RELATED APOPTOSIS INDUCING LIGAND.
Mouse: Tnfsf10, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10.
Human: TNFSF10, UNCHARACTERIZED PROTEIN TNFSF10.
Human: TNFSF10, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10.
Human: TNFSF10, 6 KDA PROTEIN.
Human: TNFSF10, TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 10 SPLICE VARIANT.
Human: TNFSF10, 14 KDA PROTEIN.

Annotations for TNFSF10 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS 
membraneCIEA IEA IEA IEA 
integral to membraneCRCA ISS 
extracellular spaceCIEA IEA 
soluble fractionCTAS 
zinc ion bindingFIEA 
protein bindingFIPI ISS 
tumor necrosis factor receptor bindingFIEA IEA IEA 
cytokine activityFIEA IEA 
metal ion bindingFIEA 
signal transducer activityFIEP 
apoptosisPIEA IEA IEA 
signal transductionPTAS TAS 
induction of apoptosisPTAS NAS 
positive regulation of I-kappaB kinase/NF-kappaB cascadePIEP 
cell-cell signalingPTAS 
immune responsePIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
skeleton phenotypeMPUn
tumorigenesisMPUn
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway