IpiRecord: IPI00000075

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
secretory granule	C			IDA
extracellular space	C	ISS	RCA	ISS IDA
axon	C			IDA
cell soma	C			IDA
proteinaceous extracellular matrix	C	ISS	IDA IDA	IEA ISS
protein binding	F	ISS	TAS IPI	ISS
transforming growth factor beta receptor binding	F	ISS IEA	TAS	IC IEA TAS ISS
transcription activator activity	F	ISS	IDA IDA	IEA ISS
growth factor activity	F	IEA	IEA IEA	IEA
protein N-terminus binding	F			IMP
regulation of progression through cell cycle	P		IEA
positive regulation of cell proliferation	P	ISS	IDA	ISS
negative regulation of neuroblast proliferation	P			IDA
regulation of DNA binding	P	ISS	IDA	IEA ISS
positive regulation of isotype switching to IgA isotypes	P	IDA	ISS	IEA ISS
positive regulation of apoptosis	P			IDA
wound healing	P			IEP
striated muscle development	P		TAS	ISS
inflammatory response	P	ISS	IMP IMP	IEA ISS
positive regulation of epithelial cell proliferation	P			IDA
organ morphogenesis	P	ISS	TAS	ISS
response to organic substance	P			IDA
SMAD protein nuclear translocation	P			IDA
transforming growth factor beta receptor signaling pathway	P	ISS	IDA	ISS
morphogenesis of a branching structure	P			IDA
negative regulation of immune response	P			IDA
myelination	P			IMP
defense response to fungus, incompatible interaction	P			IDA
cell death	P	ISS	IMP IMP	IEA ISS
positive regulation of transcription, DNA-dependent	P	ISS	IDA IDA	IEA ISS
response to hypoxia	P			IEP
germ cell migration	P	IEA	IDA	IEA ISS
negative regulation of release of sequestered calcium ion into cytosol	P			IDA
activation of NF-kappaB transcription factor	P			IDA
lymph node development	P	ISS	IMP	IEA ISS
regulation of cell proliferation	P		IDA	TAS ISS
negative regulation of cell proliferation	P	ISS	TAS	ISS
defense response	P		TAS	ISS
negative regulation of progression through cell cycle	P	IDA		IEA
positive regulation of exit from mitosis	P			IDA
negative regulation of ossification	P	IEA	IDA	IEA ISS
epithelial to mesenchymal transition	P	TAS		IDA
regulation of binding	P		IDA	ISS
negative regulation of phagocytosis	P			IDA
lung development	P			TAS
cell proliferation	P		TAS TAS IDA	ISS
regulation of protein import into nucleus	P	ISS	IDA	IEA ISS
protein amino acid phosphorylation	P	ISS	IDA	IEA ISS
negative regulation of hormone secretion	P	IDA	ISS
regulation of striated muscle development	P	ISS	IDA	IEA ISS
regulation of cell growth	P			TAS
cell growth	P	IEA	IEA
regulatory T cell differentiation	P	IEA	IDA	IEA
negative regulation of transcription	P	IDA		IEA
skeletal development	P	ISS	TAS TAS	ISS
negative regulation of epithelial cell proliferation	P			IDA
response to drug	P			IEP
growth	P		IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (19)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un Un
cellular phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un Un
embryogenesis phenotype	MP		Un Un
immune system phenotype	MP		Un Un Un
lethality-embryonic/perinatal	MP		Un Un Un
lethality-postnatal	MP		Un Un Un
muscle phenotype	MP		Un
nervous system phenotype	MP		Un Un
respiratory system phenotype	MP		Un Un Un
vision/eye phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un
digestive/alimentary phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un Un Un
growth/size phenotype	MP		Un Un Un
life span-post-weaning/aging	MP		Un Un
liver/biliary system phenotype	MP		Un Un Un

Disease (11)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Osteochondrodysplasias	D			ISS
Carotid Artery Diseases	D			ISS
Obesity	D			ISSISSIEP
Hypertrophy, Right Ventricular	D			IEP
Diabetes Mellitus, Experimental	D			IEP
Myocardial Infarction	D			ISS
Arteriosclerosis	D			ISS
Heart Diseases	D			ISS
Hyperlipidemia	D			IEP
Dilatation, Pathologic	D			ISS
Hypertension	D			IEP

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (7)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
TGF-beta signaling pathway (04350)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cell cycle (04110)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway