IpiRecord: IPI00000299

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cellular_component	C			ND
insulin receptor binding	F	IEA	IEA	IMP
phosphoinositide 3-kinase binding	F			IMP IPI
signal transducer activity	F	TAS TAS	IEA	ISS
receptor activity	F		IEA	IEA
protein domain specific binding	F			IPI
protein binding	F	IPI	IPI	ISS
protein kinase binding	F	IEA	IDA	ISS
response to peptide hormone stimulus	P			IDA
positive regulation of cell proliferation	P	NR		ISS
glucose metabolic process	P	TAS		ISS
signal transduction	P	TAS	IEA	ISS
cell proliferation	P	IEA	IMP	ISS
insulin receptor signaling pathway	P	IEA	IMP	IMP ISS
brain development	P	IEA	IMP	ISS ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (16)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
cellular phenotype	MP		Un
adipose tissue phenotype	MP		Un Un Un Un Un
behavior/neurological phenotype	MP		Un Un Un
homeostasis/metabolism phenotype	MP		Un Un Un Un Un
endocrine/exocrine gland phenotype	MP		Un Un Un Un Un Un
lethality-postnatal	MP		Un
renal/urinary system phenotype	MP		Un
nervous system phenotype	MP		Un
normal phenotype	MP		Un
cardiovascular system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un Un Un Un
reproductive system phenotype	MP		Un Un Un
pigmentation phenotype	MP		Un
growth/size phenotype	MP		Un Un Un Un Un
life span-post-weaning/aging	MP		Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus, Non-Insulin-Dependent	D			ISS
Insulin Resistance	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
insulin signaling pathway	W			IDAIMP

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway