IpiRecord: IPI00000513

IPI00000513 - CDH1, E-CADHERIN.
Uniprot Accession: Q9UII8
Uniprot ID: Q9UII8_HUMAN
Mapping: Chr 16, 67328696 - 67426943
Entrez Gene: 999
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14014)
Rat: Cdh1, EPITHELIAL CADHERIN PRECURSOR.
Mouse: Cdh1, EPITHELIAL CADHERIN PRECURSOR.
Human: CDH1, E-CADHERIN.
Human: CDH1, EPITHELIAL CADHERIN PRECURSOR.
Human: CDH1, E-CADHERIN.

Annotations for CDH1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCIDA IDA IDA IDA IDA IDA ISS IDA IEA 
extracellular spaceCRCA ISS 
cell junctionCIEA IEA 
cell-cell adherens junctionCIDA IDA IDA IDA IDA ISS IEA 
basolateral plasma membraneCIDA ISS IEA 
apical part of cellCIDA ISS IEA 
membraneCIEA IEA IEA 
adherens junctionCIDA ISS 
cytoplasmCIDA 
integral to membraneCIEA NAS RCA ISS ISS IEA 
beta-catenin bindingFIPI ISS IEA 
calcium ion bindingFIEA IDA ISS IEA 
protein bindingFIEA IPI IPI IPI IPI IPI IPI IPI ISS IDA 
molecular_functionFND 
homophilic cell adhesionPIEA NAS IEA ISS IEA 
cell adhesionPIEA IEA 
response to toxinPIEP 
cell-cell adhesionPIMP ISS 
response to organic substancePIEP 
protein homooligomerizationPIDA ISS IEA 
regulation of caspase activityPIDA ISS IEA 
response to drugPIEP 
protein metabolic processPIDA ISS IEA 
synaptogenesisPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn Un
embryogenesis phenotypeMPUn Un Un
lethality-embryonic/perinatalMPUn Un Un Un
tumorigenesisMPUn
cardiovascular system phenotypeMPUn
normal phenotypeMPUn
reproductive system phenotypeMPUn Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Lung NeoplasmsDIED
Bladder NeoplasmsDIEP
Cleft LipDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EHEC (05130)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
Adherens junction (04520)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pathogenic Escherichia coli infection - EPEC (05131)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway