IpiRecord: IPI00000690

IPI00000690 - AIFM1, ISOFORM 1 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q1L6K6
Uniprot ID: Q1L6K6_HUMAN
Mapping: Chr X, 129091018 - 129127489
Entrez Gene: 9131
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14994)
Rat: Pdcd8, APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR.
Mouse: Aifm1, APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR.
Mouse: Aifm1, PROGRAMMED CELL DEATH 8.
Rat: Pdcd8, APOPTOSIS-INDUCING FACTOR.
Human: AIFM1, ISOFORM 1 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR.
Human: AIFM1, ISOFORM 3 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR.
Human: AIFM1, ISOFORM 2 OF APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL PRECURSOR.

Annotations for AIFM1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrial outer membraneCTAS ISS 
soluble fractionCIDA ISS 
cytoplasmCIEA IEA 
cytosolCTAS ISS 
nucleusCIDA TAS IDA ISS ISS IEA 
microsomeCIDA ISS 
mitochondrionCIDA IDA IDA IDA ISS ISS IEA 
mitochondrial intermembrane spaceCTAS ISS 
FAD bindingFIEA IEA 
electron carrier activityFISS 
electron-transferring-flavoprotein dehydrogenase activityFTAS ISS 
protein bindingFISS 
oxidoreductase activityFIEA IEA IEA 
DNA bindingFIEA IEA 
DNA damage response, signal transduction resulting in induction of apoptosisPISS 
apoptosisPIEA IEA 
DNA fragmentation during apoptosisPTAS IPI ISS ISS 
apoptotic mitochondrial changesPTAS ISS 
apoptotic chromosome condensationPIPI 
cell redox homeostasisPIEA IEA 
electron transportPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
cellular phenotypeMPUn Un
behavior/neurological phenotypeMPUn Un
homeostasis/metabolism phenotypeMPUn Un
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
muscle phenotypeMPUn Un
nervous system phenotypeMPUn Un
vision/eye phenotypeMPUn
cardiovascular system phenotypeMPUn Un
growth/size phenotypeMPUn Un
life span-post-weaning/agingMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Apoptosis (04210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway