| IPI00001560 - CDKN2A, CYCLIN-DEPENDENT KINASE INHIBITOR. | |
|---|---|
| Uniprot Accession: A7LNE7 | |
| Uniprot ID: A7LNE7_HUMAN | |
| Mapping: Chr 9, 21957751 - 21984490 | |
| Entrez Gene: 1029 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5502) |
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| Rat: Cdkn2a, CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORM 2. |
| Mouse: Cdkn2a, ISOFORM 2 OF CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORMS 1/2. |
| Mouse: Cdkn2a, CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORM 3. |
| Mouse: Cdkn2a, ISOFORM 1 OF CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORMS 1/2. |
| Rat: Cdkn2a, CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORM 1. |
| Human: CDKN2A, CYCLIN-DEPENDENT KINASE INHIBITOR. |
| Human: CDKN2A, ISOFORM 3 OF CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORMS 1/2/3. |
| Human: CDKN2A, CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORM 4. |
| Human: CDKN2A, ISOFORM 2 OF CYCLIN-DEPENDENT KINASE INHIBITOR 2A, ISOFORMS 1/2/3. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleoplasm | C | IEA | IDA | ISS |
| cytoplasm | C | IEA | IDA | ISS |
| nucleus | C | IEA | IEA | NAS IEA IDA |
| cellular_component | C | ND | ||
| nucleolus | C | IEA | IDA IDA IDA IDA IDA | ISS |
| protein binding | F | IPI IPI IPI | IPI | ISS |
| kinase activity | F | IEA | ||
| transcription factor activity | F | IDA RCA | ISS | |
| cyclin-dependent protein kinase inhibitor activity | F | IEA | IDA IDA | TAS ISS |
| DNA binding | F | IEA | RCA | ISS IEA |
| negative regulation of cyclin-dependent protein kinase activity | P | IEA | IDA | ISS |
| negative regulation of immature T cell proliferation in the thymus | P | IMP | ||
| negative regulation of progression through cell cycle | P | IEA | TAS IEA | |
| rRNA processing | P | IEA | IEA | IEA |
| cell cycle arrest | P | IEA | IDA | ISS |
| apoptosis | P | IEA | IEA | IEA |
| somatic stem cell division | P | IMP | ||
| cell aging | P | IEA | IDA | ISS |
| cell cycle | P | NAS | IEA | IEA |
| negative regulation of B cell proliferation | P | IMP | ||
| epidermis development | P | IEA | IMP | ISS |
| regulation of cyclin-dependent protein kinase activity | P | IDA | ISS | |
| transcription | P | IEA | IEA | IEA |
| response to drug | P | IEP | ||
| aging | P | IMP | ISS IEP | |
| regulation of transcription, DNA-dependent | P | IEA | IDA RCA | ISS IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un | ||
| nervous system phenotype | MP | Un Un | ||
| vision/eye phenotype | MP | Un Un | ||
| tumorigenesis | MP | Un Un Un Un Un Un Un | ||
| hematopoietic system phenotype | MP | Un | ||
| life span-post-weaning/aging | MP | Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Kidney Neoplasms | D | IAGP | ||
| Stomach Neoplasms | D | IAGP | ||
| Lung Neoplasms | D | IAGP | ||
| Carcinoma, Hepatocellular | D | IAGPIEP | ||
| Tongue Neoplasms | D | IAGP | ||
| Melanoma | D | ISS | ||
| Esophageal Neoplasms | D | IEP | ||
| Colonic Neoplasms | D | IEP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Glioma (05214) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Chronic myeloid leukemia (05220) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Cell cycle (04110) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |
| Pancreatic cancer (05212) | Present in KEGG pathway | Not present in KEGG pathway | Present in KEGG pathway |