IpiRecord: IPI00002185

IPI00002185 - HTR2A, 5-HYDROXYTRYPTAMINE RECEPTOR 2A.
Uniprot Accession: Q9P2Q9
Uniprot ID: Q9P2Q9_HUMAN
Mapping: Chr 13, 46305514 - 46368179
Entrez Gene: 3356
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12508)
Rat: Htr2a, 5-HYDROXYTRYPTAMINE RECEPTOR 2A.
Mouse: Htr2a, 5-HYDROXYTRYPTAMINE RECEPTOR 2A.
Human: HTR2A, 5-HYDROXYTRYPTAMINE RECEPTOR 2A.

Annotations for HTR2A and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
dendriteCIDA 
cytoplasmCIDA 
integral to plasma membraneCTAS ISS 
integral to membraneCRCA ISS IEA 
membraneCIEA IEA IEA 
receptor activityFIEA IEA IEA 
G-protein coupled receptor activityFIEA 
rhodopsin-like receptor activityFIEA IEA IEA 
protein complex bindingFIPI 
signal transducer activityFIEA 
serotonin receptor activityFTAS RCA ISS ISS 
positive regulation of MAPK activityPIMP 
regulation of dopamine secretionPIMP 
cell deathPIMP 
serotonin receptor signaling pathwayPTAS ISS 
serotonin receptor, phospholipase C activating pathwayPIDA 
synaptic transmissionPTAS ISS 
G-protein coupled receptor protein signaling pathwayPIEA IEA IEA 
negative regulation of synaptic transmission, glutamatergicPIMP 
thermoregulationPIMP 
positive regulation of vasoconstrictionPIMP 
memoryPIMP 
positive regulation of cell proliferationPIMP 
response to stressPIMP 
sleepPIMP 
negative regulation of potassium ion transportPIMP 
signal transductionPIEA IEA IEA 
sensory perception of painPIMP 
response to drugPIMP 
agingPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
behavior/neurological phenotypeMPUn
muscle phenotypeMPUn
digestive/alimentary phenotypeMPUn

Disease (9)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
PancreatitisDIED
ObesityDISSISS
AnoxiaDIEP
Insulin ResistanceDISS
HyperphagiaDIED
Back PainDIED
Heart Failure, CongestiveDIED
HyperglycemiaDIED
HypertensionDISSISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Neuroactive ligand-receptor interaction (04080)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway