IpiRecord: IPI00002412

IPI00002412 - PPT1, PALMITOYL-PROTEIN THIOESTERASE 1 PRECURSOR.
Uniprot Accession: Q6FGQ4
Uniprot ID: Q6FGQ4_HUMAN
Mapping: Chr 1, 40310964 - 40335962
Entrez Gene: 5538
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5894)
Rat: Ppt1, PALMITOYL-PROTEIN THIOESTERASE 1 PRECURSOR.
Mouse: Ppt1, PPT1 PROTEIN.
Mouse: Ppt1, PALMITOYL-PROTEIN THIOESTERASE.
Mouse: Ppt1, FULL INSERT SEQUENCE.
Mouse: Ppt1, SEQUENCE.
Human: PPT1, PALMITOYL-PROTEIN THIOESTERASE 1 PRECURSOR.
Human: PPT1, PALMITOYL-PROTEIN THIOESTERASE 1.
Human: PPT1, PALMITOYL-PROTEIN THIOESTERASE 1.
Human: PPT1, PALMITOYL-PROTEIN THIOESTERASE 1.

Annotations for PPT1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
axonCIDA IDA ISS 
Golgi apparatusCIDA ISS 
cytosolCISS ISS 
extracellular regionCIDA ISS ISS ISS 
lysosomeCISS IDA IDA IDA IMP IDA ISS ISS 
extracellular spaceCRCA IDA ISS 
dendriteCIDA IEA 
membrane fractionCISS IDA 
neuron projectionCIDA 
cell somaCIDA IDA IEA 
nucleusCIDA ISS 
lipid raftCIDA ISS 
synaptic vesicleCIDA IDA ISS 
synapseCIDA 
hydrolase activityFIEA IEA IEA 
palmitoyl-(protein) hydrolase activityFIDA IDA ISS IMP IEA IMP IMP IDA ISS ISS ISS 
palmitoyl-CoA hydrolase activityFISS IDA ISS ISS 
positive regulation of pinocytosisPIMP ISS 
lipid catabolic processPIDA ISS 
protein catabolic processPNAS 
lipid raft organization and biogenesisPIMP ISS 
protein transportPIMP ISS 
visual perceptionPIEA IMP IEA 
DNA fragmentation during apoptosisPIDA ISS 
regulation of synaptic plasticityPTAS 
positive regulation of receptor mediated endocytosisPIMP ISS 
negative regulation of neuron apoptosisPIMP IMP ISS 
associative learningPIMP IEA 
cellular macromolecule catabolic processPIMP 
negative regulation of cell growthPIMP ISS 
adult locomotory behaviorPIMP IMP ISS IEA 
cellular protein catabolic processPIMP IEA 
grooming behaviorPIMP ISS IEA 
neurotransmitter secretionPIMP IEA 
protein depalmitoylationPIDA IDA ISS IMP IMP ISS ISS 
regulation of synapse structure and activityPNAS 
sphingolipid catabolic processPTAS 
lysosome organization and biogenesisPIMP IMP 
cofactor metabolic processPIMP ISS 
cofactor transportPIMP ISS 
neuron developmentPTAS 
protein modification processPIEA IEA IEA 
nervous system developmentPIMP ISS ISS 
receptor-mediated endocytosisPIMP ISS 
lysosomal lumen acidificationPIMP ISS 
response to stimulusPIEA 
pinocytosisPIMP ISS 
regulation of phospholipase A2 activityPIMP 
brain developmentPIEP IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
behavior/neurological phenotypeMPUn Un
immune system phenotypeMPUn
skeleton phenotypeMPUn
muscle phenotypeMPUn Un
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn Un
vision/eye phenotypeMPUn
hematopoietic system phenotypeMPUn
life span-post-weaning/agingMPUn Un
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Fatty acid elongation in mitochondria (00062)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway