IpiRecord: IPI00002519
| IPI00002519 - SHMT1, ISOFORM 1 OF SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC. | |
|---|---|
| Uniprot Accession: Q96HY0 | |
| Uniprot ID: Q96HY0_HUMAN | |
| Mapping: Chr 17, 18171920 - 18207581 | |
| Entrez Gene: 6470 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9465) |
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| Rat: Shmt1, SERINE HYDROXYMETHYLTRANSFERASE. |
| Mouse: Shmt1, SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC. |
| Mouse: Shmt1, SERINE HYDROXYMETHYLTRANSFERASE 1. |
| Rat: Shmt1, SERINE HYDROXYMETHYLTRANSFERASE (FRAGMENT). |
| Human: SHMT1, ISOFORM 1 OF SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC. |
| Human: SHMT1, 14 KDA PROTEIN. |
| Human: SHMT1, ISOFORM 2 OF SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC. |
| Human: SHMT1, ISOFORM 3 OF SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC. |
| Human: SHMT1, CYTOSOLIC SERINE HYDROXYMETHYLTRANSFERASE. |
| Human: SHMT1, 49 KDA PROTEIN. |
| Human: SHMT1, 14 KDA PROTEIN. |
Annotations for SHMT1 and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cytoplasm | C | IEA | ||
| mitochondrion | C | IDA | ISS | |
| cytosol | C | TAS ISS | ||
| methyltransferase activity | F | IEA | ||
| catalytic activity | F | IEA | IEA | IEA |
| pyridoxal phosphate binding | F | IEA | IEA | IEA TAS |
| glycine hydroxymethyltransferase activity | F | IEA | IEA | IEA TAS |
| transferase activity | F | IEA | IEA | |
| L-serine metabolic process | P | IEA | IEA | IEA TAS |
| L-serine catabolic process | P | ISS | ||
| one-carbon compound metabolic process | P | IEA | ||
| glycine metabolic process | P | IEA | IEA | IEA TAS |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (0)
There are no Mammalian Phenotype Ontology annotations for this protein in the database
Disease (0)
There are no Disease Ontology annotations for this protein in the database
Pathway (3)
Compiled Pathway Ontology Annotations (from IPI)
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| folate mediated one-carbon metabolic pathway | W | TAS | ||
| pathway of folate cycle/metabolism | W | TAS | ||
| glycine, serine and threonine metabolic pathway | W | TAS |
KEGG Pathway (5)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| One carbon pool by folate (00670) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Glycine, serine and threonine metabolism (00260) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Lysine degradation (00310) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Methane metabolism (00680) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
| Cyanoamino acid metabolism (00460) | Present in KEGG pathway | Present in KEGG pathway | Not present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute