IpiRecord: IPI00003099

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular region	C	TAS	IEA	IEA
extracellular space	C		IDA IDA IDA IDA IDA IDA	IEA ISS IDA
growth factor activity	F		IEA IEA
interleukin-2 receptor binding	F	TAS	IDA IDA IDA ISS	IEA ISS ISS IMP
kappa-type opioid receptor binding	F			IMP
cytokine activity	F		IDA IDA ISS	IEA ISS
glycosphingolipid binding	F			IDA
kinase activator activity	F	TAS
protein binding	F		IPI	IEA ISS
carbohydrate binding	F			IDA
positive regulation of cell growth	P	TAS
negative regulation of heart contraction	P			IDA
immune response	P	TAS	IEA IEA	IEA
negative regulation of lymphocyte proliferation	P		IMP	IEA
positive regulation of protein amino acid phosphorylation	P			IDA
positive regulation of T cell differentiation	P			IDA
negative regulation of inflammatory response	P		IMP IMP	IEA ISS
positive regulation of regulatory T cell differentiation	P			IDA
positive regulation of cell proliferation	P	TAS
T cell differentiation	P	TAS
positive regulation of transcription from RNA polymerase II promoter	P		IDA	IEA ISS
regulation of T cell homeostatic proliferation	P		IMP	IEA
G-protein coupled receptor protein signaling pathway	P			IMP
cell-cell signaling	P	TAS
anti-apoptosis	P	TAS
positive regulation of isotype switching to IgG isotypes	P		IMP	IEA ISS
positive regulation of tyrosine phosphorylation of Stat5 protein	P		IDA	IEA ISS
positive regulation of activated T cell proliferation	P		IDA IDA ISS IMP	IEA ISS
positive regulation of immunoglobulin secretion	P		IMP	IEA ISS
protein kinase C activation	P			IMP
positive regulation of T cell proliferation	P		IDA	ISS IDA
elevation of cytosolic calcium ion concentration	P			IDA
natural killer cell activation	P	TAS
negative regulation of protein amino acid phosphorylation	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
immune system phenotype	MP		Un
tumorigenesis	MP		Un
digestive/alimentary phenotype	MP		Un
hematopoietic system phenotype	MP		Un
no phenotypic analysis	MP		Un
growth/size phenotype	MP		Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Severe Combined Immunodeficiency	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type I diabetes mellitus (04940)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway