IpiRecord: IPI00003479

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
insoluble fraction	C			IDA
nucleus	C	IEA	IDA IDA IDA	ISS
cytosol	C			IDA
cytoplasm	C	IEA	IDA IDA IDA	ISS
protein kinase activity	F		IDA	ISS
kinase activity	F		IDA IDA	TAS ISS
protein-tyrosine kinase activity	F			ISS
protein binding	F	IPI IPI IPI	IPI IPI IPI	ISS
MAP kinase activity	F	TAS	IDA TAS IMP IDA IDA	TAS ISS ISS IEA
transferase activity	F	IEA	IEA	IEA
protein serine/threonine kinase activity	F	IEA	ISS	IEA
phosphotyrosine binding	F	IEA	IMP	ISS
ATP binding	F	IEA	IEA IEA	IEA
nucleotide binding	F	IEA	IEA	IEA
intracellular signaling cascade	P			IDA
protein kinase cascade	P			TAS
peptidyl-serine phosphorylation	P		ISS
response to lipopolysaccharide	P	IEA	IDA
positive regulation of transcription	P			IEP
synaptic transmission	P	TAS		ISS
response to chemical stimulus	P			IDA
lipopolysaccharide-mediated signaling pathway	P	IEA	IDA
response to exogenous dsRNA	P	IEA	IDA
protein amino acid phosphorylation	P	IEA	IDA IDA IDA	TAS ISS IEA
positive regulation of cell proliferation	P			IEP
MAPKKK cascade	P	IEA	IDA	ISS
cell cycle	P	IEA	IEA	IEA
response to stress	P			ISS
chemotaxis	P	TAS		ISS
induction of apoptosis	P	TAS		ISS
cytosine metabolic process	P	IEA	IDA	ISS
signal transduction	P	TAS	TAS	IDA ISS ISS
negative regulation of cell differentiation	P	IEA	IGI
sensory perception of pain	P			IMP
organ morphogenesis	P	IEA	IDA	ISS
phosphorylation	P		TAS	ISS
nuclear translocation of MAPK	P			IDA
positive regulation of cell migration	P			IEP
response to DNA damage stimulus	P	IEA	IDA	ISS
response to estrogen stimulus	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (12)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
growth/size phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un
other phenotype	MP		Un
embryogenesis phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un Un
immune system phenotype	MP		Un
cardiovascular system phenotype	MP		Un
hematopoietic system phenotype	MP		Un
muscle phenotype	MP		Un
embryonic lethality	N			ISS
absent extraembryonic ectoderm	N			ISS
absent ectoplacental cone	N			ISS

Disease (5)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Coronary Restenosis	D			IED
Cardiomegaly	D			IED
Myocardial Infarction	D			IED
Brain Ischemia	D			ISS
Myocardial Reperfusion Injury	D			IED

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
The extracellular signal-regulated RAF/MEK/ERK pathway	W			IDAIMP

KEGG Pathway (22)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
GnRH signaling pathway (04912)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Long-term depression (04730)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
mTOR signaling pathway (04150)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Toll-like receptor signaling pathway (04620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
TGF-beta signaling pathway (04350)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adherens junction (04520)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type II diabetes mellitus (04930)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Axon guidance (04360)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Gap junction (04540)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Dorso-ventral axis formation (04320)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Long-term potentiation (04720)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway