IpiRecord: IPI00003494

IPI00003494 - PTTG1, SECURIN.
Uniprot Accession: Q6IAL9
Uniprot ID: Q6IAL9_HUMAN
Mapping: Chr 5, 159781418 - 159788323
Entrez Gene: 9232
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9311)
Rat: Pttg1, SECURIN.
Mouse: Pttg1, ISOFORM 1 OF SECURIN.
Mouse: Pttg1, ISOFORM 2 OF SECURIN.
Mouse: Pttg1, 21 KDA PROTEIN.
Human: PTTG1, SECURIN.
Human: PTTG1, PITUITARY TUMOR TRANSFORMING GENE PROTEIN.

Annotations for PTTG1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cellular_componentCND 
nucleusCTAS IEA IEA IEA ISS IEA 
cytoplasmCTAS IEA IEA IEA ISS IEA 
transcription factor activityFTAS ISS 
protein bindingFIPI ISS 
cysteine protease inhibitor activityFNAS IDA ISS ISS IEA 
molecular_functionFND 
mitosisPIEA IEA IEA 
negative regulation of cell proliferationPIMP 
homologous chromosome segregationPIEA IDA ISS IEA 
DNA repairPIEA IEA IEA 
cellular processPISS 
chromosome organization and biogenesisPIEA IEA IEA 
chromosome segregationPIEA IEA IEA 
regulation of cell growthPIMP 
DNA metabolic processPIEA IEA 
spermatogenesisPTAS ISS 
cell cyclePIEA IEA IEA 
transcription from RNA polymerase II promoterPTAS ISS 
cell divisionPIEA IEA IEA 
response to DNA damage stimulusPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (16)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
adipose tissue phenotypeMPUn
cellular phenotypeMPUn Un Un
behavior/neurological phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un Un
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn
reproductive system phenotypeMPUn Un
life span-post-weaning/agingMPUn
growth/size phenotypeMPUn Un Un
no phenotypic analysisMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway