IpiRecord: IPI00003783

IPI00003783 - MAP2K2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Uniprot Accession: Q7Z370
Uniprot ID: Q7Z370_HUMAN
Mapping: Chr 19, 4041331 - 4075126
Entrez Gene: 5605
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_6761)
Rat: Map2k2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Mouse: Map2k2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Mouse: Map2k2, KINASE 2, FULL INSERT SEQUENCE.
Mouse: Map2k2, FULL INSERT SEQUENCE.
Mouse: Map2k2, MITOGEN ACTIVATED PROTEIN KINASE KINASE 2.
Rat: Map2k2, 27 KDA PROTEIN.
Human: MAP2K2, DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2.
Human: MAP2K2, 34 KDA PROTEIN.

Annotations for MAP2K2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular regionCNAS 
transferase activityFIEA IEA IEA 
ATP bindingFNAS IEA IEA IEA IEA 
protein serine/threonine kinase activityFNAS IEA IEA IEA IEA 
protein bindingFIPI 
kinase activityFIEA 
protein-tyrosine kinase activityFIEA IEA IEA 
protein kinase activityFIEA 
nucleotide bindingFIEA IEA IEA 
protein amino acid phosphorylationPNAS IEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
lethality-embryonic/perinatalMPUn
vision/eye phenotypeMPUn
digestive/alimentary phenotypeMPUn
normal phenotypeMPUn
hearing/vestibular/ear phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
The extracellular signal-regulated RAF/MEK/ERK pathwayWNASIMP

KEGG Pathway (13)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Insulin signaling pathway (04910)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway