IPI report for IPI00003970

IpiRecord: IPI00003970

IPI00003970 - ME3, NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q8TBJ0
Uniprot ID: Q8TBJ0_HUMAN
Mapping: Chr 11, 85829798 - 86061075
Entrez Gene: 10873
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: Q16798 UniProtKB/Swiss-Prot: MAON_HUMAN REFSEQ_REVIEWED: NP_001014811 REFSEQ_REVIEWED: GI:62420882 REFSEQ_REVIEWED: NP_006671 REFSEQ_REVIEWED: GI:62420880 UniProtKB/TrEMBL: Q8TBJ0 UniProtKB/TrEMBL: Q8TBJ0_HUMAN ENSEMBL: ENSP00000352657 ENSEMBL: ENSG00000151376 H-InvDB: HIT000323746 UniParc: UPI000012EBAC HGNC: 6985 Entrez Gene: 10873 UniGene: Hs.199743 CCDS: CCDS8277.1 trome: HTR008783 UTRdb: BB007122 UTRdb: BB281988 UTRdb: CC165645 RZPD: Hs.199743 CleanEx: HS_ME3 InterPro: IPR015884 InterPro: IPR012301 InterPro: IPR012302 InterPro: IPR001891 Pfam: PF00390 Pfam: PF03949 PRINTS: PR00072 PROSITE: PS00331

IPI00003970 - ME3, NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR.

Uniprot Accession: Q8TBJ0

Uniprot ID: Q8TBJ0_HUMAN

Mapping: Chr 11, 85829798 - 86061075

Entrez Gene: 10873

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_891)
Rat: Me3_predicted, SIMILAR TO MALIC ENZYME 3, NADP(+)-DEPENDENT, MITOCHONDRIAL.
Mouse: Me3, NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR.
Mouse: Me3, CLONE:1700020C08 PRODUCT:SIMILAR TO MALIC ENZYME.
Mouse: Me3, 37 KDA PROTEIN.
Rat: Me3_predicted, 29 KDA PROTEIN.
Rat: Me3_predicted, SIMILAR TO MALIC ENZYME 3, NADP(+)-DEPENDENT, MITOCHONDRIAL ISOFORM 1.
Rat: Me3_predicted, SIMILAR TO MALIC ENZYME 3, NADP(+)-DEPENDENT, MITOCHONDRIAL ISOFORM 2.
Human: ME3, NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR.
Human: ME3, MITOCHONDRIAL NADP(+)-DEPENDENT MALIC ENZYME 3.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_891)

Rat: Me3_predicted, SIMILAR TO MALIC ENZYME 3, NADP(+)-DEPENDENT, MITOCHONDRIAL.

Mouse: Me3, NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR.

Mouse: Me3, CLONE:1700020C08 PRODUCT:SIMILAR TO MALIC ENZYME.

Mouse: Me3, 37 KDA PROTEIN.

Rat: Me3_predicted, 29 KDA PROTEIN.

Rat: Me3_predicted, SIMILAR TO MALIC ENZYME 3, NADP(+)-DEPENDENT, MITOCHONDRIAL ISOFORM 1.

Rat: Me3_predicted, SIMILAR TO MALIC ENZYME 3, NADP(+)-DEPENDENT, MITOCHONDRIAL ISOFORM 2.

Human: ME3, NADP-DEPENDENT MALIC ENZYME, MITOCHONDRIAL PRECURSOR.

Human: ME3, MITOCHONDRIAL NADP(+)-DEPENDENT MALIC ENZYME 3.

Annotations for ME3 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
mitochondrion	C	TAS	IEA	ISS
NAD binding	F	IEA	IEA	IEA
metal ion binding	F	IEA	IEA
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity	F	IDA	IEA	ISS
oxidoreductase activity	F	IEA	IEA
malic enzyme activity	F	IEA	IEA	IEA
cofactor binding	F	TAS		ISS
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	F	IEA	IEA	IEA
pyruvate metabolic process	P	IDA		ISS
aerobic respiration	P	TAS		ISS
malate metabolic process	P	IDA IEA	IEA	ISS IEA
electron transport	P	IDA		ISS
oxygen and reactive oxygen species metabolic process	P	TAS		ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Carbon fixation (00710)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway
Pyruvate metabolism (00620)	Present in KEGG pathway	Present in KEGG pathway	Not present in KEGG pathway