IpiRecord: IPI00004509

IPI00004509 - LTC4S, LEUKOTRIENE C4 SYNTHASE.
Uniprot Accession: Q9UD18
Uniprot ID: Q9UD18_HUMAN
Mapping: Chr 5, 179092457 - 179156119
Entrez Gene: 4056
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9383)
Rat: Ltc4s, LEUKOTRIENE C4 SYNTHASE.
Mouse: Ltc4s, LEUKOTRIENE C4 SYNTHASE.
Mouse: Ltc4s, LTC4S PROTEIN.
Mouse: Ltc4s, LEUKOTRIENE C4 SYNTHASE.
Human: LTC4S, LEUKOTRIENE C4 SYNTHASE.
Human: MAML1, MASTERMIND-LIKE PROTEIN 1.
Human: LTC4S, MASTERMIND-LIKE 1 VARIANT (FRAGMENT).
Mouse: Maml1, MASTERMIND-LIKE PROTEIN 1.
Rat: Maml1_predicted, SIMILAR TO MASTERMIND-LIKE PROTEIN 1.
Rat: Maml1_predicted, SIMILAR TO MASTERMIND-LIKE PROTEIN 1.

Annotations for LTC4S and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IDA IDA ISS ISS ISS 
integral to membraneCTAS RCA IEA ISS 
membraneCIEA IEA 
extracellular spaceCRCA ISS 
microsomeCTAS 
membrane fractionCTAS 
transcription coactivator activityFIEA IDA IDA ISS ISS ISS 
glutathione transferase activityFTAS 
lyase activityFIEA IEA 
leukotriene-C4 synthase activityFTAS IEA IDA IDA 
enzyme activator activityFIEA IEA IEA 
regulation of transcription, DNA-dependentPIEA IEA 
positive regulation of transcription from RNA polymerase II promoterPIEA IDA IDA ISS ISS ISS 
transcriptionPIEA IEA 
leukotriene biosynthetic processPIEA IEA TAS 
leukotriene metabolic processPIEA IEA 
Notch signaling pathwayPIEA IDA IDA ISS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn Un
lethality-postnatalMPUn Un
muscle phenotypeMPUn Un
respiratory system phenotypeMPUn
cardiovascular system phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
eicosanoids metabolic pathwayWIEA

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Arachidonic acid metabolism (00590)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Notch signaling pathway (04330)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway