IpiRecord: IPI00004653

IPI00004653 - FIGF, VASCULAR ENDOTHELIAL GROWTH FACTOR D PRECURSOR.
Uniprot Accession: Q53FX1
Uniprot ID: Q53FX1_HUMAN
Mapping: Chr X, 15273640 - 15312498
Entrez Gene: 2277
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14859)
Rat: Figf, VASCULAR ENDOTHELIAL GROWTH FACTOR D PRECURSOR.
Mouse: Figf, VASCULAR ENDOTHELIAL GROWTH FACTOR D PRECURSOR.
Human: FIGF, VASCULAR ENDOTHELIAL GROWTH FACTOR D PRECURSOR.

Annotations for FIGF and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCTAS IDA ISS 
extracellular regionCIEA IDA ISS IEA 
membraneCIEA IEA IEA 
vascular endothelial growth factor receptor 3 bindingFIDA 
platelet-derived growth factor receptor bindingFTAS ISS 
protein bindingFIPI ISS IEA 
protein homodimerization activityFIPI 
vascular endothelial growth factor receptor bindingFIMP ISS 
vascular endothelial growth factor receptor 2 bindingFIDA 
growth factor activityFIEA IDA TAS ISS IEA 
cell differentiationPIEA IEA IEA 
cell proliferationPIEA IDA ISS IEA 
positive regulation of angiogenesisPTAS 
regulation of progression through cell cyclePIEA IEA IEA 
positive regulation of cell proliferationPTAS IDA ISS 
lymphangiogenesisPISS 
angiogenesisPIEA IEA IEA 
vascular endothelial growth factor receptor signaling pathwayPIGI IMP 
multicellular organismal developmentPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (2)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
normal phenotypeMPUn
increased angiogenesisNIEA

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
vascular endothelial growth factor signaling pathwayWIMP

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
mTOR signaling pathway (04150)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Pancreatic cancer (05212)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway