IpiRecord: IPI00005731

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cellular_component	C			ND
integral to membrane	C	TAS	RCA	ISS ISS IEA
membrane	C	IEA	IEA IEA	IEA
receptor activity	F	IEA	IEA	IEA
metal ion binding	F		IEA
nucleotide binding	F	IEA	IEA	IEA
SMAD binding	F	IDA
protein serine/threonine kinase activity	F		IEA IEA
ATP binding	F	IDA	IEA IEA	IEA
kinase activity	F		IEA
protein-tyrosine kinase activity	F			ISS
manganese ion binding	F	IEA	IEA	IEA
magnesium ion binding	F	IEA	IEA	IEA
transmembrane receptor protein serine/threonine kinase activity	F		IEA
transforming growth factor beta receptor activity	F	IEA	IEA IEA	IEA
protein kinase activity	F		IEA
receptor signaling protein serine/threonine kinase activity	F		IEA
molecular_function	F			ND
transferase activity	F	IEA	IEA	IEA
protein amino acid phosphorylation	P	IDA	IEA	IEA
cell differentiation	P		IGI	ISS
lung development	P		IMP	ISS
mesendoderm development	P		IMP	ISS
cartilage development	P		IMP	ISS
transforming growth factor beta receptor signaling pathway	P	TAS		ISS
hindlimb morphogenesis	P		IMP	ISS
positive regulation of epithelial cell proliferation	P		IMP	ISS
heart development	P		IMP	ISS
anterior/posterior pattern formation	P		IMP	ISS
dorsal/ventral axis specification	P		IMP	ISS
ectoderm development	P		IMP	ISS
Mullerian duct regression	P		IMP	ISS
transmembrane receptor protein serine/threonine kinase signaling pathway	P		IEA	IEA
dorsal/ventral pattern formation	P		IGI	ISS
biological_process	P			ND
endoderm development	P		IMP	ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (23)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
craniofacial phenotype	MP		Un
skin/coat/nails phenotype	MP		Un Un
behavior/neurological phenotype	MP		Un
immune system phenotype	MP		Un
embryogenesis phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un
skeleton phenotype	MP		Un
lethality-postnatal	MP		Un Un
muscle phenotype	MP		Un Un
nervous system phenotype	MP		Un Un
tumorigenesis	MP		Un
vision/eye phenotype	MP		Un Un
normal phenotype	MP		Un
cardiovascular system phenotype	MP		Un Un
limbs/digits/tail phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
reproductive system phenotype	MP		Un Un
life span-post-weaning/aging	MP		Un
growth/size phenotype	MP		Un Un
pigmentation phenotype	MP		Un Un
no phenotypic analysis	MP		Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Intestinal Diseases	D			ISSISSISS
Hamartoma	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
TGF-beta signaling pathway (04350)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway