| IPI00006036 - PDX1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1. | |
|---|---|
| Uniprot Accession: Q5VYW2 | |
| Uniprot ID: Q5VYW2_HUMAN | |
| Mapping: Chr 13, 27392157 - 27397394 | |
| Entrez Gene: 3651 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11175) |
|---|
| Rat: Pdx1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1. |
| Mouse: Pdx1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1. |
| Human: PDX1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IEA | IDA IDA IC IDA | IEA ISS IDA |
| protein homodimerization activity | F | IDA | ||
| transcription activator activity | F | IEA | IDA | ISS IDA |
| DNA binding | F | IDA IDA IDA | ISS | |
| sequence-specific DNA binding | F | IEA | IEA | IEA IDA |
| specific RNA polymerase II transcription factor activity | F | TAS | ISS | |
| transcription factor activity | F | IEA | IDA | IEA TAS ISS IDA IMP |
| glucose metabolic process | P | IEA | IDA | ISS |
| regulation of transcription | P | IEA | ||
| regulation of transcription, DNA-dependent | P | IDA | IEA TAS ISS | |
| generation of precursor metabolites and energy | P | TAS | ISS | |
| regulation of cell proliferation | P | IEA | IDA | ISS |
| cell differentiation | P | IEA | IMP | ISS |
| transcription, DNA-dependent | P | IMP | ||
| regulation of transcription from RNA polymerase II promoter | P | IMP | ISS | |
| organ morphogenesis | P | TAS | ISS | |
| positive regulation of transcription from RNA polymerase II promoter | P | IEA | IDA | ISS IDA |
| transcription from RNA polymerase II promoter | P | IDA IMP | ||
| protein heterooligomerization | P | IDA | ||
| multicellular organismal development | P | IEA | IEA | |
| pancreas development | P | IEA | IMP | ISS |
| transcription | P | IEA |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un | ||
| skin/coat/nails phenotype | MP | Un | ||
| endocrine/exocrine gland phenotype | MP | Un Un Un Un Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un Un Un | ||
| immune system phenotype | MP | Un | ||
| lethality-postnatal | MP | Un Un Un | ||
| renal/urinary system phenotype | MP | Un Un | ||
| normal phenotype | MP | Un | ||
| digestive/alimentary phenotype | MP | Un Un Un Un Un | ||
| growth/size phenotype | MP | Un Un Un | ||
| liver/biliary system phenotype | MP | Un Un |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Type II diabetes mellitus (04930) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Maturity onset diabetes of the young (04950) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |