IpiRecord: IPI00006036

IPI00006036 - PDX1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1.
Uniprot Accession: Q5VYW2
Uniprot ID: Q5VYW2_HUMAN
Mapping: Chr 13, 27392157 - 27397394
Entrez Gene: 3651
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11175)
Rat: Pdx1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1.
Mouse: Pdx1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1.
Human: PDX1, PANCREAS/DUODENUM HOMEOBOX PROTEIN 1.

Annotations for PDX1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IDA IDA IC IDA IEA ISS IDA 
protein homodimerization activityFIDA 
transcription activator activityFIEA IDA ISS IDA 
DNA bindingFIDA IDA IDA ISS 
sequence-specific DNA bindingFIEA IEA IEA IDA 
specific RNA polymerase II transcription factor activityFTAS ISS 
transcription factor activityFIEA IDA IEA TAS ISS IDA IMP 
glucose metabolic processPIEA IDA ISS 
regulation of transcriptionPIEA 
regulation of transcription, DNA-dependentPIDA IEA TAS ISS 
generation of precursor metabolites and energyPTAS ISS 
regulation of cell proliferationPIEA IDA ISS 
cell differentiationPIEA IMP ISS 
transcription, DNA-dependentPIMP 
regulation of transcription from RNA polymerase II promoterPIMP ISS 
organ morphogenesisPTAS ISS 
positive regulation of transcription from RNA polymerase II promoterPIEA IDA ISS IDA 
transcription from RNA polymerase II promoterPIDA IMP 
protein heterooligomerizationPIDA 
multicellular organismal developmentPIEA IEA 
pancreas developmentPIEA IMP ISS 
transcriptionPIEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
skin/coat/nails phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn Un Un Un Un
homeostasis/metabolism phenotypeMPUn Un Un Un Un
immune system phenotypeMPUn
lethality-postnatalMPUn Un Un
renal/urinary system phenotypeMPUn Un
normal phenotypeMPUn
digestive/alimentary phenotypeMPUn Un Un Un Un
growth/size phenotypeMPUn Un Un
liver/biliary system phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Type II diabetes mellitus (04930)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Maturity onset diabetes of the young (04950)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway