IpiRecord: IPI00006608

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
neuron projection	C		IDA	ISS
Golgi apparatus	C		IDA	ISS IDA
cytoplasm	C		IDA	ISS
ciliary rootlet	C		IDA	ISS
spindle midzone	C		IDA	ISS
integral to membrane	C		IDA	ISS IEA
axon	C		IDA IDA	ISS
membrane fraction	C		IDA IDA	ISS
cytoplasmic vesicle	C		IDA IDA	ISS
perinuclear region of cytoplasm	C		IDA	ISS
coated pit	C		IEA
apical part of cell	C		IDA	ISS
membrane	C		TAS IDA	ISS
neuromuscular junction	C		IDA	ISS
iron ion binding	F		IEA
serine-type endopeptidase inhibitor activity	F		IEA IEA	IEA
protein binding	F		IPI	ISS IPI
binding	F		IEA
endopeptidase inhibitor activity	F		IEA
metal ion binding	F		IEA
heparin binding	F		IEA
protease activator activity	F			IDA
zinc ion binding	F		IEA
copper ion binding	F		IEA
DNA binding	F		IDA	ISS
apoptosis	P		IEA
regulation of body size	P		IMP	ISS
mRNA polyadenylation	P		IDA	ISS
extracellular matrix organization and biogenesis	P		IGI	ISS
neuron remodeling	P		IMP	ISS
adult locomotory behavior	P		IMP IMP IMP IMP	ISS
G2 phase of mitotic cell cycle	P		IMP	ISS
suckling behavior	P		IGI	ISS
cell adhesion	P		IEA
axonogenesis	P		IMP	ISS
regulation of translation	P		IDA
smooth endoplasmic reticulum calcium ion homeostasis	P		IGI	ISS
axon midline choice point recognition	P		IMP	ISS
regulation of synapse structure and activity	P		IMP	ISS
collateral sprouting in the absence of injury	P		IGI	ISS
dendrite development	P		IMP IGI IMP	ISS
forebrain development	P		IMP IMP	ISS
visual learning	P		IMP	ISS
induction of apoptosis	P			IDA
cellular copper ion homeostasis	P		IMP IGI	ISS
endocytosis	P		IEA
neurite development	P		IDA	ISS
positive regulation of progression through mitotic cell cycle	P		IMP	ISS
regulation of balance	P		IGI	ISS
axon cargo transport	P		IMP IMP	ISS
locomotory behavior	P		IGI	ISS
mating behavior	P		IGI	ISS
positive regulation of transcription from RNA polymerase II promoter	P		IDA IGI	ISS
Notch signaling pathway	P		IEA
synaptic growth at neuromuscular junction	P		IGI	ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
cellular phenotype	MP		Un
behavior/neurological phenotype	MP		Un Un Un
other phenotype	MP		Un Un Un
lethality-postnatal	MP		Un Un
nervous system phenotype	MP		Un Un Un Un Un Un
reproductive system phenotype	MP		Un
hearing/vestibular/ear phenotype	MP		Un
life span-post-weaning/aging	MP		Un
growth/size phenotype	MP		Un Un Un

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Alzheimer Disease	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
Alzheimer disease pathway	W			IEA

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Alzheimer's disease (05010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Neurodegenerative Disorders (01510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway