IpiRecord: IPI00006663
| IPI00006663 - ALDH2, ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR. | |
|---|---|
| Uniprot Accession: P05091 | |
| Uniprot ID: ALDH2_HUMAN | |
| Mapping: Chr 12, 110688729 - 110732165 | |
| Entrez Gene: 217 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11029) |
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| Rat: Aldh2, ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR. |
| Mouse: Aldh2, ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR. |
| Mouse: Aldh2, 21 KDA PROTEIN. |
| Rat: Aldh2, PROTEIN. |
| Human: ALDH2, ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR. |
| Human: ALDH2, 8 KDA PROTEIN. |
| Human: ALDH2, MITOCHONDRIAL ALDEHYDE DEHYDROGENASE 2 VARIANT (FRAGMENT). |
| Human: ALDH2, 12 KDA PROTEIN. |
Annotations for ALDH2 and orthologs
GO Annotation Table
Compiled GO Annotations (from IPI)
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| mitochondrion | C | IEA | IDA IEA | ISS ISS IEA |
| electron carrier activity | F | TAS | ISS | |
| aldehyde dehydrogenase [NAD(P)+] activity | F | TAS | ISS | |
| aldehyde dehydrogenase (NAD) activity | F | TAS | IEA | ISS IEA |
| oxidoreductase activity | F | IEA | IEA IEA | IEA |
| molecular_function | F | ND | ||
| 3-chloroallyl aldehyde dehydrogenase activity | F | ISS | ||
| metabolic process | P | IEA | IEA | |
| response to nicotine | P | IEP | ||
| carbohydrate metabolic process | P | TAS | ISS | |
| alcohol metabolic process | P | TAS | ISS |
Cellular Component
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Biological Process
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Molecular Function
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
Phenotype (2)
Compiled Mammalian Phenotype Ontology Annotations (from IPI)
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | # | ||
| alcohol preference | N | ISS |
Disease (6)
Compiled Disease Ontology Annotations (from IPI)
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Alzheimer Disease | D | ISS | ||
| Brain Infarction | D | ISS | ||
| Gram-Negative Bacterial Infections | D | IEP | ||
| Fatty Liver, Alcoholic | D | IED | ||
| Hypertension | D | ISSISS | ||
| Liver Diseases | D | ISS |
Pathway (15)
Compiled Pathway Ontology Annotations (from IPI)
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| ascorbate and aldarate metabolic pathway | W | IEA | ||
| fatty acid metabolic pathway | W | IEA | ||
| beta-alanine metabolic pathway | W | IEA | ||
| glycerolipid metabolic pathway | W | IEA | ||
| bile acid biosynthetic pathway | W | IEA | ||
| histidine metabolic pathway | W | IEA | ||
| arginine and proline metabolic pathway | W | IEA | ||
| glycolysis/gluconeogenesis pathway | W | IEA | ||
| pyruvate metabolic pathway | W | IEA | ||
| valine, leucine and isoleucine degradation pathway | W | IEA | ||
| limonene and pinene degradation pathway | W | IEA | ||
| butanoate metabolic pathway | W | IEA | ||
| tryptophan metabolic pathway | W | IEA | ||
| lysine degradation pathway | W | IEA | ||
| propanoate metabolic pathway | W | IEA |
KEGG Pathway (15)
KEGG Pathways for this protein (from IPI)
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| beta-Alanine metabolism (00410) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Propanoate metabolism (00640) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Fatty acid metabolism (00071) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Histidine metabolism (00340) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Limonene and pinene degradation (00903) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Lysine degradation (00310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Glycolysis / Gluconeogenesis (00010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Tryptophan metabolism (00380) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Glycerolipid metabolism (00561) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Ascorbate and aldarate metabolism (00053) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Bile acid biosynthesis (00120) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Pyruvate metabolism (00620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Valine, leucine and isoleucine degradation (00280) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Butanoate metabolism (00650) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Urea cycle and metabolism of amino groups (00220) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
© MCW Proteomics Center, 2006-2008
Supported by funds from the National Heart, Lung and Blood Institute