IpiRecord: IPI00006675

IPI00006675 - ABCC4, MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 4.
Uniprot Accession: Q9BX28
Uniprot ID: Q9BX28_HUMAN
Mapping: Chr 13, 94470090 - 94751684
Entrez Gene: 10257
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_12563)
Rat: Abcc4, ATP-BINDING CASSETTE PROTEIN C4.
Mouse: Abcc4, (CFTR/MRP), MEMBER 4, FULL INSERT SEQUENCE.
Human: ABCC4, MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 4.
Human: ABCC4, ATP-BINDING CASSETTE SUBFAMILY C MEMBER 4 VARIANT 2.
Human: ABCC4, ATP-BINDING CASSETTE, SUB-FAMILY C, MEMBER 4 ISOFORM 2.

Annotations for ABCC4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membrane fractionCIDA ISS 
cellular_componentCND 
plasma membraneCIDA ISS 
membraneCIEA 
platelet dense granule membraneCIDA ISS 
integral to membraneCIEA IEA 
15-hydroxyprostaglandin dehydrogenase (NAD+) activityFNAS 
ATPase activityFIEA IEA 
ATPase activity, coupled to transmembrane movement of substancesFIEA IEA 
chloride channel activityFIEA IEA 
ATP bindingFIEA IEA IEA IEA 
multidrug efflux pump activityFTAS 
nucleotide bindingFIEA IEA IEA 
multidrug transportPTAS 
ion transportPIEA IEA 
biological_processPND 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (10)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn Un
digestive/alimentary phenotypeMPUn
cardiovascular system phenotypeMPUn Un
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn
life span-post-weaning/agingMPUn
no phenotypic analysisMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
multidrug resistance-associated protein mediated transport pathwayWISS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ABC transporters - General (02010)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway