IpiRecord: IPI00007081

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular region	C		IEA	TAS IEA
extracellular space	C		IDA IDA IDA	ISS ISS IEA
growth factor activity	F		IEA IEA
cytokine activity	F		IDA IDA IDA IDA	TAS ISS
protein binding	F		IPI	ISS IEA
hematopoietin/interferon-class (D200-domain) cytokine receptor binding	F		IEA
interleukin-4 receptor binding	F		IEA	ISS IEA
regulation of phosphorylation	P		IDA	ISS IEA
B cell activation	P		IEA	IEA
negative regulation of apoptosis	P		IDA	ISS IEA
positive regulation of isotype switching to IgE isotypes	P		IDA	ISS IEA
B cell differentiation	P			ISS
cellular defense response	P			ISS
positive regulation of peptidyl-tyrosine phosphorylation	P		IDA
connective tissue growth factor biosynthetic process	P			ISS
inflammatory response	P			NAS
positive regulation of B cell proliferation	P		IDA	ISS IEA
cholesterol metabolic process	P		IMP	IEA
negative regulation of osteoclast differentiation	P		IDA	ISS IEA
immune response	P		IEA	IEA
positive regulation of isotype switching to IgG isotypes	P		IDA IDA	ISS IEA
positive regulation of MHC class II biosynthetic process	P		IDA	ISS IEA
positive regulation of tyrosine phosphorylation of Stat5 protein	P		IDA	ISS IEA
positive regulation of activated T cell proliferation	P		IDA	ISS IEA
regulation of isotype switching	P			ISS
chemotaxis	P			ISS
positive regulation of T cell proliferation	P		IDA	ISS
T-helper 2 type immune response	P			ISS
positive regulation of transcription from RNA polymerase II promoter	P		IDA IGI	ISS IEA
regulation of immune response	P		IDA	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (11)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
immune system phenotype	MP		Un Un Un Un Un
lethality-postnatal	MP		Un
vision/eye phenotype	MP		Un
normal phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un
hematopoietic system phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un
no phenotypic analysis	MP		Un Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (5)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Hematopoietic cell lineage (04640)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway