| IPI00007118 - SERPINE1, PLASMINOGEN ACTIVATOR INHIBITOR 1 PRECURSOR. | |
|---|---|
| Uniprot Accession: P05121 | |
| Uniprot ID: PAI1_HUMAN | |
| Mapping: Chr 7, 100557172 - 100569026 | |
| Entrez Gene: 5054 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10888) |
|---|
| Rat: Serpine1, PLASMINOGEN ACTIVATOR INHIBITOR 1 PRECURSOR. |
| Mouse: Serpine1, PLASMINOGEN ACTIVATOR INHIBITOR 1 PRECURSOR. |
| Human: SERPINE1, PLASMINOGEN ACTIVATOR INHIBITOR 1 PRECURSOR. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| extracellular space | C | RCA | ISS | |
| extracellular region | C | NAS | ISS | |
| soluble fraction | C | IDA | ||
| protein binding | F | IPI IPI | IPI IPI | ISS IEA |
| serine-type endopeptidase inhibitor activity | F | IEA | IDA | ISS IEA TAS |
| endopeptidase inhibitor activity | F | IEA | ||
| plasminogen activator activity | F | IEA | IEA | IEA |
| protease binding | F | IPI | ISS IEA | |
| wound healing | P | IMP | ||
| negative regulation of proteolysis | P | TAS | ||
| fibrinolysis | P | TAS | ISS | |
| response to reactive oxygen species | P | IEP | ||
| regulation of angiogenesis | P | IEA | IDA | ISS IEA |
| glucose homeostasis | P | IEP | ||
| tissue regeneration | P | IEP | ||
| blood coagulation | P | TAS | ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| adipose tissue phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un | ||
| immune system phenotype | MP | Un | ||
| renal/urinary system phenotype | MP | Un | ||
| respiratory system phenotype | MP | Un | ||
| tumorigenesis | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| normal phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un | ||
| growth/size phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Diabetes Mellitus, Non-Insulin-Dependent | D | ISS | ||
| Venous Thrombosis | D | ISS | ||
| Coronary Arteriosclerosis | D | ISS | ||
| Diabetic Nephropathies | D | IAGP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| oxygen homeostasis pathway | W | IEP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Complement and coagulation cascades (04610) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |