IpiRecord: IPI00007207

IPI00007207 - LIPA, PRECURSOR.
Uniprot Accession: P38571-1
Uniprot ID: LICH_HUMAN
Mapping: Chr 10, 90963306 - 91164294
Entrez Gene: 3988
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1802)
Rat: Lip1, LYSOSOMAL ACID LIPASE/CHOLESTERYL ESTER HYDROLASE PRECURSOR.
Mouse: Lipa, LYSOSOMAL ACID LIPASE/CHOLESTERYL ESTER HYDROLASE PRECURSOR.
Mouse: Lipa, SEQUENCE.
Rat: Lip1, LYSOSOMAL ACID LIPASE 1.
Human: LIPA, PRECURSOR.
Human: LIPA, PRECURSOR.
Human: LIPA, LIPASE A, LYSOSOMAL ACID, CHOLESTEROL ESTERASE.
Human: LIPA, LIPASE A, LYSOSOMAL ACID, CHOLESTEROL ESTERASE.
Human: LIPA, ACID LIPASE/CHOLESTERYL ESTER HYDROLASE.

Annotations for LIPA and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
lysosomeCIEA ISS IDA IEA 
extracellular spaceCRCA ISS 
lipoprotein lipase activityFISS 
catalytic activityFIEA 
hydrolase activityFIEA IEA IEA 
sterol esterase activityFIEA IEA IEA 
lipase activityFIDA 
lipid catabolic processPIEA IEA 
lipid metabolic processPIEA IEA IEA 
protein amino acid N-linked glycosylationPISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
adipose tissue phenotypeMP#
endocrine/exocrine gland phenotypeMP#
homeostasis/metabolism phenotypeMP#
immune system phenotypeMP#
renal/urinary system phenotypeMP#
digestive/alimentary phenotypeMP#
hematopoietic system phenotypeMP#
growth/size phenotypeMP#
liver/biliary system phenotypeMP#

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Wolman DiseaseDISSISS
Cholesterol Ester Storage DiseaseDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
glycerolipid metabolic pathwayWIEA
bile acid biosynthetic pathwayWIEA

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glycerolipid metabolism (00561)Present in KEGG pathway Not present in KEGG pathwayPresent in KEGG pathway
Bile acid biosynthesis (00120)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Alkaloid biosynthesis II (00960)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway