| IPI00007641 - IRAK4, INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4. | |
|---|---|
| Uniprot Accession: Q7Z6A8 | |
| Uniprot ID: Q7Z6A8_HUMAN | |
| Mapping: Chr 12, 42439067 - 42468164 | |
| Entrez Gene: 51135 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7458) |
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| Rat: Irak4_predicted, 22 KDA PROTEIN. |
| Mouse: Irak4, INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4. |
| Mouse: Irak4, KINASE 1, FULL INSERT SEQUENCE. |
| Mouse: Irak4, KINASE 4, FULL INSERT SEQUENCE. |
| Rat: Irak4_predicted, SIMILAR TO INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4. |
| Human: IRAK4, INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4. |
| Human: IRAK4, INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE 4 MUTANT FORM 2. |
| Human: IRAK4, KINASE APK1A (FRAGMENT). |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular_component | C | ND | ||
| protein-tyrosine kinase activity | F | IEA | ||
| kinase activity | F | IEA | IEA | |
| nucleotide binding | F | IEA | IEA | |
| protein binding | F | IPI IPI IEA | IEA | IEA |
| protein serine/threonine kinase activity | F | IEA | IEA IEA | |
| magnesium ion binding | F | IEA | IEA | |
| ATP binding | F | IEA | IEA IEA | IEA |
| interleukin-1 receptor binding | F | IPI | ISS | |
| transferase activity | F | IEA | IEA | |
| protein kinase activity | F | IEA | IEA | |
| molecular_function | F | ND | ||
| receptor activity | F | IEA | IEA | |
| protein amino acid phosphorylation | P | IEA | IEA | IEA |
| cytokine production | P | IDA | ISS | |
| cytokine and chemokine mediated signaling pathway | P | IDA | IMP ISS | |
| signal transduction | P | IEA | IEA | |
| positive regulation of smooth muscle cell proliferation | P | IMP | ||
| JNK cascade | P | IMP | ||
| positive regulation of transcription from RNA polymerase II promoter | P | IMP |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un | ||
| immune system phenotype | MP | Un Un | ||
| tumorigenesis | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Bacterial Infections and Mycoses | D | ISS |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Apoptosis (04210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |