IpiRecord: IPI00008494

IPI00008494 - ICAM1, INTERCELLULAR ADHESION MOLECULE 1 PRECURSOR.
Uniprot Accession: Q5NKV8
Uniprot ID: Q5NKV8_HUMAN
Mapping: Chr 19, 10242765 - 10258291
Entrez Gene: 3383
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_7698)
Rat: Icam1, INTERCELLULAR ADHESION MOLECULE 1 PRECURSOR.
Mouse: Icam1, ISOFORM 1 OF INTERCELLULAR ADHESION MOLECULE 1 PRECURSOR.
Mouse: Icam1, ISOFORM 2 OF INTERCELLULAR ADHESION MOLECULE 1 PRECURSOR.
Rat: Icam1, 59 KDA PROTEIN.
Human: ICAM1, INTERCELLULAR ADHESION MOLECULE 1 PRECURSOR.
Human: ICAM1, CELL SURFACE GLYCOPROTEIN.
Human: ICAM1, INTERCELLULAR ADHESION MOLECULE-1 (FRAGMENT).
Human: ICAM1, SICAM-1 (FRAGMENT).

Annotations for ICAM1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCNAS IEP ISS 
integral to plasma membraneCTAS ISS 
integral to membraneCIEA IEA 
membraneCIEA IEA IEA IEA 
cell surfaceCIDA 
external side of plasma membraneCIEA IDA 
integrin bindingFIMP 
protein bindingFIEA IEA IEP IEA 
transmembrane receptor activityFTAS ISS 
activation of NF-kappaB transcription factorPIMP 
cell-cell adhesionPIEA IEA IDA IEA IMP 
positive regulation of nitric oxide biosynthetic processPIMP 
leukocyte migrationPTAS 
cell adhesionPIDA ISS 
regulation of cell adhesionPIEA IDA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
endocrine/exocrine gland phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un Un Un
muscle phenotypeMPUn
cardiovascular system phenotypeMPUn
digestive/alimentary phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un Un

Disease (4)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Crohn DiseaseDISS
ObesityDISS
Inflammatory Bowel DiseasesDISS
Diabetes Mellitus, Insulin-DependentDISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway