IPI report for IPI00008794

IpiRecord: IPI00008794

IPI00008794 - DFFB, ISOFORM ALPHA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).
Uniprot Accession: Q5SR22
Uniprot ID: Q5SR22_HUMAN
Mapping: Chr 1, 3763705 - 3791853
Entrez Gene: 1677
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: O76075-1 UniProtKB/Swiss-Prot: DFFB_HUMAN Vega: OTTHUMP00000003633 REFSEQ_REVIEWED: NP_004393 REFSEQ_REVIEWED: GI:4758150 UniProtKB/TrEMBL: Q5SR22 UniProtKB/TrEMBL: Q5SR22_HUMAN ENSEMBL: ENSP00000367454 ENSEMBL: ENSG00000169598 UniParc: UPI000006230F HGNC: 2773 Entrez Gene: 1677 UniGene: Hs.133089 CCDS: CCDS52.1 UTRdb: BB046544 UTRdb: BB097960 UTRdb: BB097961 UTRdb: BB097962 UTRdb: BB324690 UTRdb: BB324691 UTRdb: BB324693 UTRdb: BB324695 UTRdb: BB324697 UTRdb: BB324699 UTRdb: BB394852 UTRdb: CC108584 UTRdb: CC168484 UTRdb: CC300749 RZPD: Hs.133089 InterPro: IPR015311 InterPro: IPR003508 Pfam: PF02017 Pfam: PF09230 PROSITE: PS51135

IPI00008794 - DFFB, ISOFORM ALPHA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).

Uniprot Accession: Q5SR22

Uniprot ID: Q5SR22_HUMAN

Mapping: Chr 1, 3763705 - 3791853

Entrez Gene: 1677

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5673)
Rat: Dffb, DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).
Mouse: Dffb, DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).
Human: DFFB, ISOFORM ALPHA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).
Human: DFFB, ISOFORM BETA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).
Human: DFFB, ISOFORM GAMMA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).
Human: DFFB, DNAATION FACTOR, 40KDA, BETA POLYPEPTIDE.
Human: DFFB, DNAATION FACTOR B TRUNCATED FORM II.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5673)

Rat: Dffb, DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).

Mouse: Dffb, DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).

Human: DFFB, ISOFORM ALPHA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).

Human: DFFB, ISOFORM BETA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).

Human: DFFB, ISOFORM GAMMA OF DNA FRAGMENTATION FACTOR SUBUNIT BETA (FRAGMENT).

Human: DFFB, DNAATION FACTOR, 40KDA, BETA POLYPEPTIDE.

Human: DFFB, DNAATION FACTOR B TRUNCATED FORM II.

Annotations for DFFB and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Mouse	Rat
cytoplasm	C	IEA
cytosol	C		ISS
intracellular	C	IEA	IEA
nucleus	C	ISS	IEA IDA ISS
protein binding	F	IPI	IEA ISS IPI
DNA binding	F	IDA	IEA ISS
nuclease activity	F	IEA	IEA
nicotinate phosphoribosyltransferase activity	F	IDA	IEA ISS
deoxyribonuclease activity	F		IDA
hydrolase activity	F	IEA	IEA
caspase-activated deoxyribonuclease activity	F		ISS
induction of apoptosis	P		IDA
apoptosis	P	IEA IEA	IEA
DNA fragmentation during apoptosis	P	ISS	IDA ISS
intracellular signaling cascade	P		ISS

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Mouse
cellular phenotype	MP	Un
immune system phenotype	MP	Un
hematopoietic system phenotype	MP	Un
growth/size phenotype	MP	Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway