IpiRecord: IPI00008965

IPI00008965 - JUN, TRANSCRIPTION FACTOR AP-1.
Uniprot Accession: Q6FHM7
Uniprot ID: Q6FHM7_HUMAN
Mapping: Chr 1, 59019048 - 59022587
Entrez Gene: 3725
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5575)
Rat: Jun, TRANSCRIPTION FACTOR AP-1.
Mouse: Jun, TRANSCRIPTION FACTOR AP-1.
Human: JUN, TRANSCRIPTION FACTOR AP-1.

Annotations for JUN and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IDA IEA IDA ISS IDA 
transcription factor complexCIEA IDA IDA IEA IMP ISS 
intracellularCIEA 
nuclear chromosomeCTAS ISS 
protein heterodimerization activityFTAS 
transcription factor activityFTAS TAS IEA IEA ISS 
protein bindingFIPI ISS 
double-stranded DNA bindingFIDA 
protein homodimerization activityFTAS 
sequence-specific DNA bindingFIEA IEA IEA IDA 
transcription activator activityFTAS 
RNA polymerase II transcription factor activityFTAS TAS ISS 
DNA bindingFIDA IDA ISS 
protein dimerization activityFIEA IEA IEA 
regulation of progression through cell cyclePIEA IMP IEA ISS 
leading edge cell differentiationPIEA IMP IEA ISS 
negative regulation of protein amino acid autophosphorylationPIEA IMP 
cellular processPIEA IMP IEA 
transcriptionPIEA IEA 
transcription from RNA polymerase II promoterPTAS 
regulation of transcription, DNA-dependentPIEA IMP IEA ISS 
positive regulation of transcription from RNA polymerase II promoterPIEA IDA IEA ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (15)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn Un
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn Un Un Un
immune system phenotypeMPUn
lethality-embryonic/perinatalMPUn Un Un Un
skeleton phenotypeMPUn
lethality-postnatalMPUn Un
nervous system phenotypeMPUn Un Un
vision/eye phenotypeMPUn Un Un
normal phenotypeMPUn
cardiovascular system phenotypeMPUn Un
hematopoietic system phenotypeMPUn
no phenotypic analysisMPUn
growth/size phenotypeMPUn Un
liver/biliary system phenotypeMPUn Un Un

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Hodgkin DiseaseDISS
OsteopetrosisDISS

Pathway (2)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
altered c-Jun N-terminal kinase MAPK signaling pathwayWISS
c-Jun N-terminal kinases MAPK signaling pathwayWIMP

KEGG Pathway (9)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Epithelial cell signaling in Helicobacter pylori infection (05120)Present in KEGG pathway Not present in KEGG pathwayNot present in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Colorectal cancer (05210)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway