| IPI00008965 - JUN, TRANSCRIPTION FACTOR AP-1. | |
|---|---|
| Uniprot Accession: Q6FHM7 | |
| Uniprot ID: Q6FHM7_HUMAN | |
| Mapping: Chr 1, 59019048 - 59022587 | |
| Entrez Gene: 3725 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_5575) |
|---|
| Rat: Jun, TRANSCRIPTION FACTOR AP-1. |
| Mouse: Jun, TRANSCRIPTION FACTOR AP-1. |
| Human: JUN, TRANSCRIPTION FACTOR AP-1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| nucleus | C | IEA | IDA | IEA IDA ISS IDA |
| transcription factor complex | C | IEA | IDA IDA | IEA IMP ISS |
| intracellular | C | IEA | ||
| nuclear chromosome | C | TAS | ISS | |
| protein heterodimerization activity | F | TAS | ||
| transcription factor activity | F | TAS TAS | IEA | IEA ISS |
| protein binding | F | IPI | ISS | |
| double-stranded DNA binding | F | IDA | ||
| protein homodimerization activity | F | TAS | ||
| sequence-specific DNA binding | F | IEA | IEA | IEA IDA |
| transcription activator activity | F | TAS | ||
| RNA polymerase II transcription factor activity | F | TAS | TAS ISS | |
| DNA binding | F | IDA IDA | ISS | |
| protein dimerization activity | F | IEA | IEA | IEA |
| regulation of progression through cell cycle | P | IEA | IMP | IEA ISS |
| leading edge cell differentiation | P | IEA | IMP | IEA ISS |
| negative regulation of protein amino acid autophosphorylation | P | IEA | IMP | |
| cellular process | P | IEA | IMP | IEA |
| transcription | P | IEA | IEA | |
| transcription from RNA polymerase II promoter | P | TAS | ||
| regulation of transcription, DNA-dependent | P | IEA | IMP | IEA ISS |
| positive regulation of transcription from RNA polymerase II promoter | P | IEA | IDA | IEA ISS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| cellular phenotype | MP | Un Un | ||
| behavior/neurological phenotype | MP | Un | ||
| homeostasis/metabolism phenotype | MP | Un Un Un Un | ||
| immune system phenotype | MP | Un | ||
| lethality-embryonic/perinatal | MP | Un Un Un Un | ||
| skeleton phenotype | MP | Un | ||
| lethality-postnatal | MP | Un Un | ||
| nervous system phenotype | MP | Un Un Un | ||
| vision/eye phenotype | MP | Un Un Un | ||
| normal phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un Un | ||
| hematopoietic system phenotype | MP | Un | ||
| no phenotypic analysis | MP | Un | ||
| growth/size phenotype | MP | Un Un | ||
| liver/biliary system phenotype | MP | Un Un Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Hodgkin Disease | D | ISS | ||
| Osteopetrosis | D | ISS |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| altered c-Jun N-terminal kinase MAPK signaling pathway | W | ISS | ||
| c-Jun N-terminal kinases MAPK signaling pathway | W | IMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| GnRH signaling pathway (04912) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| T cell receptor signaling pathway (04660) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Epithelial cell signaling in Helicobacter pylori infection (05120) | Present in KEGG pathway | Not present in KEGG pathway | Not present in KEGG pathway |
| B cell receptor signaling pathway (04662) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Toll-like receptor signaling pathway (04620) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| MAPK signaling pathway (04010) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Wnt signaling pathway (04310) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Colorectal cancer (05210) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |
| Focal adhesion (04510) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |