| IPI00009308 - CCL2, SMALL-INDUCIBLE CYTOKINE A2 PRECURSOR. | |
|---|---|
| Uniprot Accession: P13500 | |
| Uniprot ID: CCL2_HUMAN | |
| Mapping: Chr 17, 29606409 - 29608329 | |
| Entrez Gene: 6347 | |
| Entrez MapView: |
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| +All IPI Database Cross References | |
| IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9765) |
|---|
| Rat: Ccl2, SMALL-INDUCIBLE CYTOKINE A2 PRECURSOR. |
| Mouse: Ccl2, SMALL-INDUCIBLE CYTOKINE A2 PRECURSOR. |
| Human: CCL2, SMALL-INDUCIBLE CYTOKINE A2 PRECURSOR. |
| Human: CCL2, MCP1. |
| GO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| membrane | C | IEA | ||
| cell soma | C | IDA | ||
| extracellular region | C | IEA | IEA | IEA |
| cytoplasm | C | IDA | ||
| extracellular space | C | TAS | RCA | ISS ISS IEA |
| chemokine activity | F | TAS IEA | IEA | NAS TAS ISS IEA |
| signal transducer activity | F | TAS TAS | ||
| protein kinase activity | F | TAS | ISS | |
| CCR2 chemokine receptor binding | F | IMP | ||
| protein binding | F | IPI | ISS IEA | |
| cytokine activity | F | IEA IEA | ||
| G-protein-coupled receptor binding | F | IEA | IDA IDA | ISS IEA |
| transforming growth factor beta receptor signaling pathway | P | IMP | ||
| cytokine and chemokine mediated signaling pathway | P | IMP | ||
| immune response | P | IEA | IEA | IEA |
| viral genome replication | P | TAS | ISS | |
| inflammatory response | P | IEA | IEA | IEP IEA |
| positive regulation of endothelial cell proliferation | P | IMP | ||
| cellular calcium ion homeostasis | P | TAS | ISS IDA | |
| humoral immune response | P | TAS | ISS | |
| JAK-STAT cascade | P | TAS | ISS | |
| cell-cell signaling | P | NR | ISS | |
| G-protein signaling, coupled to cyclic nucleotide second messenger | P | TAS | ISS | |
| protein amino acid phosphorylation | P | TAS | ISS | |
| response to bacterium | P | ISS | ||
| anti-apoptosis | P | IDA | ISS IEA | |
| cell adhesion | P | TAS | ISS | |
| chemotaxis | P | TAS | IEA | ISS IEA |
| organ morphogenesis | P | TAS | ISS | |
| signal transduction | P | IEA | ||
| vascular endothelial growth factor receptor signaling pathway | P | IMP | ||
| chemokinesis | P | TAS |
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| GO Graph Color Key: | Rat | Mouse | Human | Rat & Mouse | Mouse & Human | Rat & Human | Rat, Mouse & Human |
SVG image
| MP Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| immune system phenotype | MP | Un | ||
| cardiovascular system phenotype | MP | Un | ||
| hematopoietic system phenotype | MP | Un |
| DO Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Temporal Arteritis | D | ISS | ||
| Cardiovascular Diseases | D | ISS | ||
| Ischemia | D | ISS | ||
| Myocardial Infarction | D | ISS | ||
| Endomyocardial Fibrosis | D | IEP | ||
| Cerebrovascular Accident | D | ISS | ||
| Lipodystrophy | D | ISS | ||
| Heart Failure, Congestive | D | IEP |
| PW Term | Aspect | Human | Mouse | Rat |
|---|---|---|---|---|
| Angiotensin II signaling pathway | W | IEP | ||
| vascular endothelial growth factor signaling pathway | W | IMP |
| KEGG Pathway | Human | Mouse | Rat |
|---|---|---|---|
| Cytokine-cytokine receptor interaction (04060) | Present in KEGG pathway | Present in KEGG pathway | Present in KEGG pathway |