IpiRecord: IPI00009803

IPI00009803 - ITGA4, INTEGRIN ALPHA-4 PRECURSOR.
Uniprot Accession: Q8IUA2
Uniprot ID: Q8IUA2_HUMAN
Mapping: Chr 2, 182029864 - 182110711
Entrez Gene: 3676
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3374)
Rat: IPI00362823, SIMILAR TO INTEGRIN ALPHA 4.
Mouse: Itga4, INTEGRIN ALPHA-4 PRECURSOR.
Mouse: Itga4, INTEGRIN ALPHA 4.
Rat: IPI00763617, SIMILAR TO INTEGRIN ALPHA 4.
Human: ITGA4, INTEGRIN ALPHA-4 PRECURSOR.
Human: ITGA4, ITGA4 PROTEIN.

Annotations for ITGA4 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
membraneCIEA IEA 
integrin complexCIEA IEA 
integral to membraneCIEA RCA 
identical protein bindingFIPI 
calcium ion bindingFIEA IEA 
protein bindingFIEA 
receptor activityFIEA IEA 
cell adhesionPIEA IMP 
heart developmentPIMP 
integrin-mediated signaling pathwayPIEA IEA 
cell migrationPIMP IMP 
blood vessel remodelingPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
craniofacial phenotypeMPUn
immune system phenotypeMPUn Un
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
cardiovascular system phenotypeMPUn Un
hematopoietic system phenotypeMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ECM-receptor interaction (04512)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway