IpiRecord: IPI00009923

IPI00009923 - P4HA1, ISOFORM 1 OF PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 PRECURSOR.
Uniprot Accession: P13674-1
Uniprot ID: P4HA1_HUMAN
Mapping: Chr 10, 74436981 - 74526630
Entrez Gene: 5033
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14583)
Rat: P4ha1, PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 PRECURSOR.
Mouse: P4ha1, INSERT SEQUENCE.
Mouse: P4ha1, ISOFORM 2 OF PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 PRECURSOR.
Mouse: P4ha1, SEQUENCE.
Human: P4HA1, ISOFORM 1 OF PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 PRECURSOR.
Human: P4HA1, ISOFORM 2 OF PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 PRECURSOR.

Annotations for P4HA1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
extracellular spaceCRCA ISS 
endoplasmic reticulumCIEA IEA ISS 
bindingFIEA IEA 
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donorsFIEA IEA 
iron ion bindingFIEA IEA 
oxidoreductase activityFIEA IEA 
metal ion bindingFIEA IEA 
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygenFIEA IEA 
procollagen-proline 4-dioxygenase activityFIDA IEA TAS ISS ISS 
L-ascorbic acid bindingFIEA IEA 
peptidyl-proline hydroxylation to 4-hydroxy-L-prolinePIDA TAS ISS 
protein metabolic processPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMP#
cellular phenotypeMP#
other phenotypeMP#
embryogenesis phenotypeMP#
lethality-embryonic/perinatalMP#
cardiovascular system phenotypeMP#
growth/size phenotypeMP#

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Arginine and proline metabolism (00330)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway