IpiRecord: IPI00010271

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
lamellipodium	C		IDA IDA	ISS IEA
extrinsic to plasma membrane	C		IDA	ISS IEA
cytoplasm	C		IDA	ISS IEA
membrane	C		IEA
cytoplasmic membrane-bound vesicle	C		IDA IDA	ISS IEA
cell projection	C		IDA	ISS
membrane fraction	C		IDA	ISS IEA
intracellular	C	IEA	IEA	IEA
nucleotide binding	F	IEA	IEA	IEA
protein binding	F		IPI IPI IPI	IPI ISS
GTP binding	F	IEA	IDA IDA IDA	IDA ISS IEA
GTPase activity	F		IDA IDA IDA	IDA ISS
GTP-dependent protein binding	F			IEA
positive regulation of phosphoinositide 3-kinase activity	P		IMP	ISS IEA
small GTPase mediated signal transduction	P	IEA	IDA	ISS IEA
cell motility	P			IMP
protein transport	P		RCA	ISS
actin cytoskeleton organization and biogenesis	P			IDA
cell proliferation	P			IMP
dendrite development	P		IDA	ISS IEA
positive regulation of dendrite morphogenesis	P			ISS
endocytosis	P		IDA	ISS IEA
cell adhesion	P		IDA	ISS IEA
chemotaxis	P			IMP
cytoskeleton organization and biogenesis	P		IDA	ISS IEA
Rac protein signal transduction	P			TAS
cell migration	P		IDA	ISS IEA
hyperosmotic response	P		IDA	ISS IEA
lamellipodium biogenesis	P		TAS IDA	ISS IEA
positive regulation of actin filament polymerization	P		IDA	ISS IEA
bone resorption	P			IDA

Cellular Component

Biological Process

Molecular Function

Phenotype (13)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un Un
cellular phenotype	MP		Un Un
endocrine/exocrine gland phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un
embryogenesis phenotype	MP		Un
immune system phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un Un
muscle phenotype	MP		Un
cardiovascular system phenotype	MP		Un
hematopoietic system phenotype	MP		Un
reproductive system phenotype	MP		Un
growth/size phenotype	MP		Un
pigmentation phenotype	MP		Un

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Hypertrophy, Left Ventricular	D			IAGP
Cardiomegaly	D			ISSISS
Heart Failure, Congestive	D			IAGP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
the planar cell polarity Wnt signaling pathway	W			ISS

KEGG Pathway (16)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Epithelial cell signaling in Helicobacter pylori infection (05120)	Present in KEGG pathway	Not present in KEGG pathway	Not present in KEGG pathway
B cell receptor signaling pathway (04662)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Toll-like receptor signaling pathway (04620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adherens junction (04520)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Amyotrophic lateral sclerosis (ALS) (05030)	Present in KEGG pathway	Not present in KEGG pathway	Not present in KEGG pathway
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Leukocyte transendothelial migration (04670)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Wnt signaling pathway (04310)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Regulation of actin cytoskeleton (04810)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Axon guidance (04360)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway