IpiRecord: IPI00010400

IPI00010400 - PLCB3, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-3.
Uniprot Accession: A5PKZ6
Uniprot ID: A5PKZ6_HUMAN
Mapping: Chr 11, 63775623 - 63791970
Entrez Gene: 5331
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1671)
Rat: Plcb3, PHOSPHOLIPASE C BETA 3.
Mouse: Plcb3, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-3.
Mouse: Plcb3, SEQUENCE.
Human: PLCB3, 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE BETA-3.
Human: PLCB3, SIMILAR TO PHOSPHOLIPASE C, BETA 3 (FRAGMENT).

Annotations for PLCB3 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
insoluble fractionCIDA 
membraneCIEA 
nucleusCIEA 
cytosolCIDA 
calcium ion bindingFIEA IEA IEA IEA 
hydrolase activityFIEA IEA IEA 
phosphoinositide phospholipase C activityFIEA IEA IEA IDA 
signal transducer activityFIEA IEA NAS 
phospholipase C activityFIEA TAS 
phospholipid catabolic processPIDA 
lipid metabolic processPIEA IEA 
intracellular signaling cascadePIEA IEA NAS 
lipid catabolic processPIEA IEA IEA 
signal transductionPIEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
behavior/neurological phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
embryogenesis phenotypeMPUn
touch/vibrissae phenotypeMPUn
lethality-embryonic/perinatalMPUn
embryonic lethalityNISS

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
Wnt signaling pathwayWIEA
inositol phosphate metabolic pathwayWIEA
phosphatidylinositol 3 kinase-Akt signaling pathwayWIEA

KEGG Pathway (8)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Inositol phosphate metabolism (00562)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway