IPI report for IPI00010410

IpiRecord: IPI00010410

IPI00010410 - HLA-DOB, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN PRECURSOR.
Uniprot Accession: Q6FHE3
Uniprot ID: Q6FHE3_HUMAN
Mapping: Chr 6, 32888518 - 32892803
Entrez Gene: 3112
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P13765 UniProtKB/Swiss-Prot: 2DOB_HUMAN Vega: OTTHUMP00000029312 Vega: OTTHUMP00000029751 REFSEQ_REVIEWED: NP_002111 REFSEQ_REVIEWED: GI:4504403 UniProtKB/TrEMBL: Q5QNS2 UniProtKB/TrEMBL: Q5QNS2_HUMAN UniProtKB/TrEMBL: Q6FHC2 UniProtKB/TrEMBL: Q6FHC2_HUMAN UniProtKB/TrEMBL: Q6FHE3 UniProtKB/TrEMBL: Q6FHE3_HUMAN ENSEMBL: ENSP00000293722 ENSEMBL: ENSG00000168399 ENSEMBL: ENSP00000364053 ENSEMBL: ENSG00000204273 H-InvDB: HIT000032601 UniParc: UPI0000000C73 HGNC: 4937 Entrez Gene: 3112 UniGene: Hs.1802 CCDS: CCDS4754.1 trome: HTR009433 UTRdb: BB005707 UTRdb: BB281402 UTRdb: BB324398 UTRdb: BB380565 UTRdb: BB380569 UTRdb: BB380661 UTRdb: BB385273 RZPD: Hs.1802 CleanEx: HS_HLA-DOB InterPro: IPR007110 InterPro: IPR013783 InterPro: IPR003006 InterPro: IPR003597 InterPro: IPR011162 InterPro: IPR014745 InterPro: IPR000353 Pfam: PF07654 Pfam: PF00969 ProDom: PD000328 SMART: SM00407 PROSITE: PS50835 PROSITE: PS00290 SUPERFAMILY: SSF54452 GENE3D: G3DSA:2.60.40.10 GENE3D: G3DSA:3.10.320.10

IPI00010410 - HLA-DOB, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN PRECURSOR.

Uniprot Accession: Q6FHE3

Uniprot ID: Q6FHE3_HUMAN

Mapping: Chr 6, 32888518 - 32892803

Entrez Gene: 3112

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14381)
Rat: RT1-DOb, RT1-DOB PROTEIN (FRAGMENT).
Mouse: H2-Ob, MHC A-BETA-2 CHAIN.
Mouse: H2-Ob, FULL INSERT SEQUENCE.
Mouse: H2-Ob, HISTOCOMPATIBILITY 2, O REGION BETA LOCUS.
Rat: RT1-DOb, 32 KDA PROTEIN.
Human: HLA-DOB, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN PRECURSOR.
Human: HLA-DOB, HLA-DOB PROTEIN.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14381)

Rat: RT1-DOb, RT1-DOB PROTEIN (FRAGMENT).

Mouse: H2-Ob, MHC A-BETA-2 CHAIN.

Mouse: H2-Ob, FULL INSERT SEQUENCE.

Mouse: H2-Ob, HISTOCOMPATIBILITY 2, O REGION BETA LOCUS.

Rat: RT1-DOb, 32 KDA PROTEIN.

Human: HLA-DOB, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DO BETA CHAIN PRECURSOR.

Human: HLA-DOB, HLA-DOB PROTEIN.

Annotations for HLA-DOB and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
lysosome	C	IDA	ISS
membrane	C	IEA	RCA	IEA
integral to membrane	C	IEA	RCA	IEA
MHC class II protein complex	C	IEA	IEA	IEA
intracellular	C		IDA
MHC class II receptor activity	F	TAS
immune response	P	IEA	RCA	IEA
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	P	IEA	IEA	IEA

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Antigen processing and presentation (04612)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cell adhesion molecules (CAMs) (04514)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Type I diabetes mellitus (04940)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway