IpiRecord: IPI00010466

IPI00010466 - PRKCB1, ISOFORM BETA-I OF PROTEIN KINASE C BETA TYPE.
Uniprot Accession: P05771-1
Uniprot ID: KPCB_HUMAN
Mapping: Chr 16, 23754823 - 24139358
Entrez Gene: 5579
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1263)
Rat: Prkcb1, ISOFORM BETA-II OF PROTEIN KINASE C BETA TYPE.
Mouse: Prkcb1, PROTEIN KINASE C BETA TYPE.
Mouse: Prkcb1, PRKCB1 PROTEIN.
Mouse: Prkcb1, 77 KDA PROTEIN.
Rat: Prkcb1, ISOFORM BETA-I OF PROTEIN KINASE C BETA TYPE.
Human: PRKCB1, ISOFORM BETA-I OF PROTEIN KINASE C BETA TYPE.
Human: PRKCB1, ISOFORM BETA-II OF PROTEIN KINASE C BETA TYPE.

Annotations for PRKCB1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
plasma membraneCISS 
cytoplasmCIDA IDA ISS ISS 
membraneCIEA 
nucleusCIDA ISS 
soluble fractionCIDA 
membrane fractionCIDA 
centrosomeCIDA 
diacylglycerol bindingFIEA 
ATP bindingFRCA ISS 
protein serine/threonine kinase activityFRCA ISS 
protein kinase C activityFIDA IDA IDA ISS ISS 
calcium ion bindingFRCA ISS 
calcium channel regulator activityFIDA ISS 
metal ion bindingFIEA 
protein kinase activityFRCA ISS 
protein bindingFIPI ISS IDA 
zinc ion bindingFIEA 
transferase activityFRCA ISS 
kinase activityFIEA 
protein-tyrosine kinase activityFISS 
nucleotide bindingFIEA 
cellular calcium ion homeostasisPIDA ISS 
calcium ion transportPIDA ISS 
protein amino acid phosphorylationPIDA IDA RCA ISS ISS 
intracellular signaling cascadePRCA NAS ISS 
regulation of dopamine secretionPIMP 
regulation of growthPIMP 
response to glucose stimulusPIEP 
positive regulation of odontogenesis (sensu Vertebrata)PIEP 
response to drugPIMP 
response to ethanolPIEP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (5)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
hematopoietic system phenotypeMPUn
behavior/neurological phenotypeMPUn
nervous system phenotypeMPUn
immune system phenotypeMPUn
immunodeficiencyNISS

Disease (15)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
HyperalgesiaDIED
Hypertrophy, Left VentricularDIED
ObesityDIEP
CardiomegalyDIED
Diabetes Mellitus, ExperimentalDIEP
Insulin ResistanceDIED
Status EpilepticusDIEP
Fetal DiseasesDIEP
Cardiomyopathy, CongestiveDISS
Myocardial Reperfusion InjuryDIED
SilicosisDIED
Heart Failure, CongestiveDIEP
HyperglycemiaDIED
Diabetic NephropathiesDIED
HypertensionDIED

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
insulin signaling pathwayWISS

KEGG Pathway (16)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glioma (05214)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
GnRH signaling pathway (04912)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term depression (04730)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
B cell receptor signaling pathway (04662)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
VEGF signaling pathway (04370)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Leukocyte transendothelial migration (04670)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Tight junction (04530)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Calcium signaling pathway (04020)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Gap junction (04540)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Long-term potentiation (04720)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Phosphatidylinositol signaling system (04070)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway