IpiRecord: IPI00010697

IPI00010697 - ITGA6, ISOFORM ALPHA-6X1X2B OF INTEGRIN ALPHA-6 PRECURSOR.
Uniprot Accession: P23229-1
Uniprot ID: ITA6_HUMAN
Mapping: Chr 2, 173000616 - 173079256
Entrez Gene: 3655
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_3321)
Rat: Itga6, SIMILAR TO INTEGRIN ALPHA 6 ISOFORM 2.
Mouse: Itga6, ISOFORM ALPHA-6X1A OF INTEGRIN ALPHA-6 PRECURSOR.
Mouse: Itga6, CLONE:9330162A08 PRODUCT:INTEGRIN ALPHA 6, FULL INSERT SEQUENCE.
Mouse: Itga6, ISOFORM ALPHA-6X1B OF INTEGRIN ALPHA-6 PRECURSOR.
Mouse: Itga6, ITGA6 PROTEIN.
Mouse: Itga6, SEQUENCE.
Rat: Itga6, 4.
Rat: Itga6, SIMILAR TO INTEGRIN ALPHA 6 ISOFORM 1.
Rat: Itga6, 3.
Human: ITGA6, ISOFORM ALPHA-6X1X2B OF INTEGRIN ALPHA-6 PRECURSOR.
Human: ITGA6, ISOFORM ALPHA-6X1A OF INTEGRIN ALPHA-6 PRECURSOR.
Human: ITGA6, ISOFORM ALPHA-6X1B OF INTEGRIN ALPHA-6 PRECURSOR.
Human: ITGA6, ISOFORM ALPHA-6X2A OF INTEGRIN ALPHA-6 PRECURSOR.
Human: ITGA6, ISOFORM ALPHA-6X2B OF INTEGRIN ALPHA-6 PRECURSOR.
Human: ITGA6, ISOFORM ALPHA-6X1X2A OF INTEGRIN ALPHA-6 PRECURSOR.

Annotations for ITGA6 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integrin complexCIDA IEA ISS 
cell-cell adherens junctionCIDA 
basolateral plasma membraneCIDA ISS 
integral to membraneCRCA IEA ISS 
membraneCIEA 
plasma membraneCIDA IDA IDA ISS 
laminin bindingFIPI 
protein bindingFIEA IPI 
receptor activityFIEA IEA 
calcium ion bindingFIEA 
cell adhesionPIEA IEA IEA 
integrin-mediated signaling pathwayPIEA IEA 
cell-matrix adhesionPIMP ISS ISS 
cell-substrate junction assemblyPISS 
filopodium formationPIMP ISS 
leukocyte migrationPIGI IMP 
odontogenesis (sensu Vertebrata)PIMP ISS 
cell-cell adhesionPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (14)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
craniofacial phenotypeMPUn
endocrine/exocrine gland phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
renal/urinary system phenotypeMPUn
nervous system phenotypeMPUn
respiratory system phenotypeMPUn
vision/eye phenotypeMPUn
digestive/alimentary phenotypeMPUn
limbs/digits/tail phenotypeMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Epidermolysis Bullosa, JunctionalDISS
Neoplasm MetastasisDIEP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
integrin signaling pathwayWISS

KEGG Pathway (6)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
ECM-receptor interaction (04512)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell adhesion molecules (CAMs) (04514)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Hematopoietic cell lineage (04640)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cell Communication (01430)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Focal adhesion (04510)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway