IpiRecord: IPI00010717

IPI00010717 - MVK, MEVALONATE KINASE.
Uniprot Accession: Q59ET9
Uniprot ID: Q59ET9_HUMAN
Mapping: Chr 12, 108496995 - 108519450
Entrez Gene: 4598
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11173)
Rat: Mvk, MEVALONATE KINASE.
Mouse: Mvk, CLONE:G530004O05 PRODUCT:MEVALONATE KINASE, FULL INSERT SEQUENCE.
Mouse: Mvk, MEVALONATE KINASE.
Mouse: Mvk, 29 KDA PROTEIN.
Human: MVK, MEVALONATE KINASE.
Human: MVK, 12 KDA PROTEIN.
Human: MVK, 12 KDA PROTEIN.
Human: MVK, 28 KDA PROTEIN.
Human: MVK, 13 KDA PROTEIN.

Annotations for MVK and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
peroxisomeCIEA IEA IEA 
cytoplasmCIEA IEA IEA IEA 
soluble fractionCIDA 
kinase activityFIEA IEA 
mRNA bindingFIDA 
phosphotransferase activity, alcohol group as acceptorFIEA 
ATP bindingFIEA IEA IEA IEA ISS IDA 
mevalonate kinase activityFTAS IEA IDA IEA ISS ISS ISS IDA 
transferase activityFIEA IEA IEA 
identical protein bindingFIPI ISS 
nucleotide bindingFIEA IEA IEA 
regulation of cholesterol biosynthetic processPNAS 
sterol biosynthetic processPIEA 
sterol metabolic processPTAS 
metabolic processPIEA IEA IEA 
isoprenoid metabolic processPTAS 
protein amino acid phosphorylationPNR ISS 
cholesterol biosynthetic processPIEA IEA IEA TAS 
isoprenoid biosynthetic processPTAS IEA IEA IEA ISS 
lipid biosynthetic processPIEA 
phosphorylationPIEA IEA IEA 
steroid biosynthetic processPIEA 
negative regulation of protein biosynthetic processPIDA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Lipid Metabolism, Inborn ErrorsDISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
steroid biosynthetic pathwayWIEA

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Biosynthesis of steroids (00100)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway