IpiRecord: IPI00010737

IPI00010737 - THBD, THROMBOMODULIN PRECURSOR.
Uniprot Accession: P07204
Uniprot ID: TRBM_HUMAN
Mapping: Chr 20, 22974270 - 22978287
Entrez Gene: 7056
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4001)
Rat: Thbd, THROMBOMODULIN.
Mouse: Thbd, THROMBOMODULIN PRECURSOR.
Human: THBD, THROMBOMODULIN PRECURSOR.

Annotations for THBD and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS 
integral to membraneCRCA ISS 
extracellular spaceCRCA ISS IDA 
membraneCIEA IEA IEA 
cell surfaceCTAS 
plasma membraneCTAS IDA ISS 
calcium ion bindingFTAS IEA IEA 
transmembrane receptor activityFIEA IEA IEA 
protein domain specific bindingFISS 
protease bindingFISS 
protein bindingFIPI 
receptor activityFIEA 
molecular_functionFND 
sugar bindingFIEA IEA IEA 
response to cAMPPIEP 
response to lipopolysaccharidePIEP 
embryonic developmentPIEA IMP ISS 
female pregnancyPIEA IMP ISS 
response to X-rayPIEP 
blood coagulationPTAS TAS IDA ISS IEA 
negative regulation of coagulationPTAS ISS ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
immune system phenotypeMPUn
embryogenesis phenotypeMPUn Un
lethality-embryonic/perinatalMPUn Un
cardiovascular system phenotypeMPUn Un Un
normal phenotypeMPUn
life span-post-weaning/agingMPUn

Disease (13)

Compiled Disease Ontology Annotations (from IPI)

DO Term Aspect Human Mouse Rat
Cardiovascular DiseasesDTAS
ObesityDISS
Hypertension, PulmonaryDISS
Vascular DiseasesDTAS
Metabolic Syndrome XDISS
Liver Failure, AcuteDIEP
Diabetes Mellitus, ExperimentalDIEP
Autoimmune DiseasesDTAS
Respiratory Distress Syndrome, AdultDIEP
Coronary ArteriosclerosisDISS
Hyperlipidemia, Familial CombinedDISS
EndotoxemiaDIEP
HypertensionDISSIEP

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
protein C anticoagulant pathwayWTAS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Complement and coagulation cascades (04610)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway