IpiRecord: IPI00011107

IPI00011107 - IDH2, ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q53GL5
Uniprot ID: Q53GL5_HUMAN
Mapping: Chr 15, 88428220 - 88446712
Entrez Gene: 3418
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_798)
Rat: LOC361596, ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR.
Mouse: Idh2, ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR.
Mouse: Idh2, 33 KDA PROTEIN.
Human: IDH2, ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL PRECURSOR.

Annotations for IDH2 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
mitochondrial inner membraneCIEA IDA IEA 
mitochondrionCIEA IDA IEA 
manganese ion bindingFIEA IEA IEA 
metal ion bindingFIEA 
isocitrate dehydrogenase (NADP+) activityFIEA IDA IEA 
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorFIEA IEA IEA 
magnesium ion bindingFIEA IEA IEA 
oxidoreductase activityFIEA IEA IEA 
metabolic processPIEA IEA IEA 
response to stressPIEA 
carbohydrate metabolic processPNAS 
tricarboxylic acid cyclePIEA IEA IEA 
glyoxylate cyclePIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Glutathione metabolism (00480)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
Citrate cycle (TCA cycle) (00020)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway
Reductive carboxylate cycle (CO2 fixation) (00720)Present in KEGG pathway Present in KEGG pathwayNot present in KEGG pathway