IPI report for IPI00011276

IpiRecord: IPI00011276

IPI00011276 - BCKDHB, 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL PRECURSOR.
Uniprot Accession: Q9BQL0
Uniprot ID: Q9BQL0_HUMAN
Mapping: Chr 6, 80873083 - 81112706
Entrez Gene: 594
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: P21953 UniProtKB/Swiss-Prot: ODBB_HUMAN Vega: OTTHUMP00000018048 Vega: OTTHUMP00000018049 ENSEMBL_HAVANA: ENSP00000348880 ENSEMBL_HAVANA: ENSG00000083123 REFSEQ_REVIEWED: NP_000047 REFSEQ_REVIEWED: GI:4557353 REFSEQ_REVIEWED: NP_898871 REFSEQ_REVIEWED: GI:34101272 UniProtKB/TrEMBL: Q6LCK9 UniProtKB/TrEMBL: Q6LCK9_HUMAN UniProtKB/TrEMBL: Q9BQL0 UniProtKB/TrEMBL: Q9BQL0_HUMAN ENSEMBL: ENSP00000318351 ENSEMBL: ENSG00000083123 H-InvDB: HIT000220180 UniParc: UPI0000001C97 HGNC: 987 Entrez Gene: 594 UniGene: Hs.436387 UniGene: Hs.654441 CCDS: CCDS4994.1 trome: HTR004227 UTRdb: BB009557 UTRdb: BB318623 UTRdb: CC002785 UTRdb: CC354914 UTRdb: CC440694 RZPD: Hs.436387 CleanEx: HS_BCKDHB InterPro: IPR005476 InterPro: IPR009014 InterPro: IPR005475 InterPro: IPR015941 Pfam: PF02779 Pfam: PF02780 SUPERFAMILY: SSF52922 GENE3D: G3DSA:3.40.50.920

IPI00011276 - BCKDHB, 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL PRECURSOR.

Uniprot Accession: Q9BQL0

Uniprot ID: Q9BQL0_HUMAN

Mapping: Chr 6, 80873083 - 81112706

Entrez Gene: 594

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8183)
Rat: Bckdhb, PRECURSOR.
Mouse: Bckdhb, BRANCHED CHAIN KETOACID DEHYDROGENASE E1, BETA POLYPEPTIDE.
Mouse: Bckdhb, BETA POLYPEPTIDE, FULL INSERT SEQUENCE (FRAGMENT).
Human: BCKDHB, 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL PRECURSOR.
Human: BCKDHB, BRANCHED CHAIN KETO ACID DEHYDROGENASE E1, BETA POLYPEPTIDE.
Human: BCKDHB, (FRAGMENT).

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_8183)

Rat: Bckdhb, PRECURSOR.

Mouse: Bckdhb, BRANCHED CHAIN KETOACID DEHYDROGENASE E1, BETA POLYPEPTIDE.

Mouse: Bckdhb, BETA POLYPEPTIDE, FULL INSERT SEQUENCE (FRAGMENT).

Human: BCKDHB, 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL PRECURSOR.

Human: BCKDHB, BRANCHED CHAIN KETO ACID DEHYDROGENASE E1, BETA POLYPEPTIDE.

Human: BCKDHB, (FRAGMENT).

Annotations for BCKDHB and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C		RCA	ISS
mitochondrial inner membrane	C		TAS	ISS
mitochondrial alpha-ketoglutarate dehydrogenase complex	C	IMP	RCA	ISS ISS
cellular_component	C			ND
mitochondrion	C	IMP	RCA	ISS ISS
protein complex binding	F			IPI
protein binding	F	IPI
carboxy-lyase activity	F	TAS
oxidoreductase activity	F	IEA	RCA	ISS
transketolase activity	F		RCA	ISS
alpha-ketoacid dehydrogenase activity	F		IDA	ISS IEA
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	F	TAS	RCA	ISS ISS IEA
response to cAMP	P			IEP
metabolic process	P	IEA
branched chain family amino acid catabolic process	P	IMP		ISS ISS
amino acid catabolic process	P		TAS	ISS
response to glucocorticoid stimulus	P			IEP
response to nutrient	P			IEP

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (0)

There are no Mammalian Phenotype Ontology annotations for this protein in the database

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Diabetes Mellitus, Experimental	D			IEP
Maple Syrup Urine Disease	D			ISS

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Valine, leucine and isoleucine degradation (00280)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway