IpiRecord: IPI00011286

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
plasma membrane	C	TAS		ISS
integral to membrane	C		IEA IEA	IEA
integral to plasma membrane	C	TAS		ISS
membrane	C		IEA	IEA
membrane fraction	C	IEA	IDA	ISS
receptor complex	C	IDA		ISS ISS
cellular_component	C			ND
adrenoceptor activity	F		RCA	ISS
receptor activity	F	IEA	IEA	IEA
beta3-adrenergic receptor activity	F	IMP		ISS ISS ISS
beta-adrenergic receptor activity	F		IEA
epinephrine binding	F			IDA
rhodopsin-like receptor activity	F	IEA	IEA	IEA
G-protein coupled receptor activity	F		IEA
protein homodimerization activity	F	IDA		ISS ISS
beta-3 adrenergic receptor binding	F	IEA	IDA IDA	ISS
norepinephrine binding	F	IDA		IDA ISS ISS
signal transducer activity	F		IEA
positive regulation of MAPKKK cascade	P	IDA		ISS ISS
energy reserve metabolic process	P	TAS		ISS
G-protein coupled receptor protein signaling pathway	P		IEA IEA	IEA
negative regulation of body size	P	IEA	IGI	ISS
heat generation	P	IEA	IGI	ISS
norepinephrine-epinephrine vasodilation during regulation of blood pressure	P	IEA	IDA	ISS
G-protein signaling, coupled to cAMP nucleotide second messenger	P			ISS
adenylate cyclase activation	P	IDA		ISS ISS
G-protein signaling, adenylate cyclase activating pathway	P		IDA	IDA ISS
carbohydrate metabolic process	P	TAS		ISS
brown fat cell differentiation	P	IEA	IGI	ISS
receptor-mediated endocytosis	P	IDA
signal transduction	P	IEA	IEA	IEA
diet induced thermogenesis	P	IEA	IGI	ISS
arrestin mediated desensitization of G-protein coupled receptor protein signaling pathway	P	IDA
response to cold	P	IEA	IGI IGI	ISS
generation of precursor metabolites and energy	P	TAS		ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
adipose tissue phenotype	MP		Un Un
endocrine/exocrine gland phenotype	MP		Un
behavior/neurological phenotype	MP		Un
growth/size phenotype	MP		Un Un
homeostasis/metabolism phenotype	MP		Un Un
weight gain	N			ISS
obese	N			ISS

Disease (3)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Obesity	D			ISS
Insulin Resistance	D			ISS
Coronary Disease	D			ISSISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
G protein signaling pathway via Galphas family	W			ISS

KEGG Pathway (2)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Calcium signaling pathway (04020)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway