IPI report for IPI00011569

IpiRecord: IPI00011569

IPI00011569 - ACACA, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.
Uniprot Accession: Q13085-1
Uniprot ID: COA1_HUMAN
Mapping: Chr 17, 32516046 - 32841015
Entrez Gene: 31
Entrez MapView:
+All IPI Database Cross References UniProtKB/Swiss-Prot: Q13085-1 UniProtKB/Swiss-Prot: COA1_HUMAN Vega: OTTHUMP00000164076 Vega: OTTHUMP00000180727 REFSEQ_REVIEWED: NP_942133 REFSEQ_REVIEWED: GI:38679967 REFSEQ_REVIEWED: NP_942136 REFSEQ_REVIEWED: GI:38679977 ENSEMBL: ENSP00000354565 ENSEMBL: ENSG00000132142 H-InvDB: HIT000251156 UniParc: UPI000020007E HGNC: 84 Entrez Gene: 31 UniGene: Hs.160556 UTRdb: BB206570 UTRdb: BB234652 UTRdb: BB234653 UTRdb: BB305203 UTRdb: CC164857 UTRdb: CC262850 RZPD: Hs.160556 InterPro: IPR013537 InterPro: IPR011761 InterPro: IPR013816 InterPro: IPR011764 InterPro: IPR001882 InterPro: IPR005482 InterPro: IPR000089 InterPro: IPR000022 InterPro: IPR011763 InterPro: IPR011762 InterPro: IPR005481 InterPro: IPR005479 InterPro: IPR013817 InterPro: IPR011054 InterPro: IPR011053 Pfam: PF08326 Pfam: PF02785 Pfam: PF00364 Pfam: PF01039 Pfam: PF00289 Pfam: PF02786 PROSITE: PS50975 PROSITE: PS50979 PROSITE: PS00188 PROSITE: PS50968 PROSITE: PS50989 PROSITE: PS50980 PROSITE: PS00866 PROSITE: PS00867 SUPERFAMILY: SSF51230 SUPERFAMILY: SSF51246 GENE3D: G3DSA:3.30.470.20 GENE3D: G3DSA:3.40.50.20

IPI00011569 - ACACA, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.

Uniprot Accession: Q13085-1

Uniprot ID: COA1_HUMAN

Mapping: Chr 17, 32516046 - 32841015

Entrez Gene: 31

Entrez MapView: Geneprod

+All IPI Database Cross References

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9752)
Rat: Acaca, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.
Mouse: Acaca, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.
Mouse: Acaca, 8 KDA PROTEIN.
Mouse: Acaca, 4 KDA PROTEIN.
Mouse: Acaca, 22 KDA PROTEIN.
Mouse: Acaca, 13 KDA PROTEIN.
Mouse: Acaca, ISOFORM 2 OF ACETYL-COA CARBOXYLASE 1.
Rat: Acaca, ISOFORM 2 OF ACETYL-COA CARBOXYLASE 1.
Rat: Acaca, 4 KDA PROTEIN.
Human: ACACA, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.
Human: ACACA, ISOFORM 4 OF ACETYL-COA CARBOXYLASE 1.
Human: ACACA, ACETYL-COA CARBOXYLASE 1 (FRAGMENT).
Human: ACACA, ISOFORM 3 OF ACETYL-COA CARBOXYLASE 1.
Human: ACACA, 13 KDA PROTEIN.
Human: ACACA, 260 KDA PROTEIN.
Human: ACACA, 265 KDA PROTEIN.
Human: ACACA, 13 KDA PROTEIN.
Human: ACACA, 5 KDA PROTEIN.
Human: ACACA, 5 KDA PROTEIN.
Human: ACACA, ACETYL-COA CARBOXYLASE 1 (FRAGMENT).
Human: ACACA, ISOFORM 2 OF ACETYL-COA CARBOXYLASE 1.

IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_9752)

Rat: Acaca, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.

Mouse: Acaca, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.

Mouse: Acaca, 8 KDA PROTEIN.

Mouse: Acaca, 4 KDA PROTEIN.

Mouse: Acaca, 22 KDA PROTEIN.

Mouse: Acaca, 13 KDA PROTEIN.

Mouse: Acaca, ISOFORM 2 OF ACETYL-COA CARBOXYLASE 1.

Rat: Acaca, ISOFORM 2 OF ACETYL-COA CARBOXYLASE 1.

Rat: Acaca, 4 KDA PROTEIN.

Human: ACACA, ISOFORM 1 OF ACETYL-COA CARBOXYLASE 1.

Human: ACACA, ISOFORM 4 OF ACETYL-COA CARBOXYLASE 1.

Human: ACACA, ACETYL-COA CARBOXYLASE 1 (FRAGMENT).

Human: ACACA, ISOFORM 3 OF ACETYL-COA CARBOXYLASE 1.

Human: ACACA, 13 KDA PROTEIN.

Human: ACACA, 260 KDA PROTEIN.

Human: ACACA, 265 KDA PROTEIN.

Human: ACACA, 13 KDA PROTEIN.

Human: ACACA, 5 KDA PROTEIN.

Human: ACACA, ACETYL-COA CARBOXYLASE 1 (FRAGMENT).

Human: ACACA, ISOFORM 2 OF ACETYL-COA CARBOXYLASE 1.

Annotations for ACACA and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytoplasm	C		IEA
soluble fraction	C			IDA
manganese ion binding	F		IEA
ATP binding	F	IEA	IEA IEA	IDA
biotin carboxylase activity	F		IEA
nucleotide binding	F		IEA
ligase activity	F	IEA	IEA IEA
metal ion binding	F		IEA
acetyl-CoA carboxylase activity	F		IMP	ISS ISS ISS IDA IMP
biotin binding	F	IEA	IEA	IMP
catalytic activity	F		IEA IEA
response to organic cyclic substance	P			IMP
lipid biosynthetic process	P		IEA
metabolic process	P	IEA	IEA
acetyl-CoA metabolic process	P			IDA
fatty acid biosynthetic process	P		IEA
response to drug	P			IEP

Cellular Component

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key:

Rat

Mouse

Human

Rat & Mouse

Mouse & Human

Rat & Human

Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Mouse	Rat
growth/size phenotype	MP	Un
homeostasis/metabolism phenotype	MP	Un Un
embryogenesis phenotype	MP	Un Un
liver/biliary system phenotype	MP	Un
lethality-embryonic/perinatal	MP	Un Un
deafness	N		ISS

Disease (2)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Insulin Resistance	D			IED
Fatty Liver	D			IED

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Rat
fatty acid biosynthetic pathway	W	IEA
pyruvate metabolic pathway	W	IEA
propanoate metabolic pathway	W	IEA

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Propanoate metabolism (00640)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pyruvate metabolism (00620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fatty acid biosynthesis (00061)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway