IpiRecord: IPI00011866

IPI00011866 - FGF1, FIBROBLAST GROWTH FACTOR 1 (ACIDIC) ISOFORM 2 PRECURSOR.
Uniprot Accession: Q16588
Uniprot ID: Q16588_HUMAN
Mapping: Chr 5, 141951927 - 142046134
Entrez Gene: 2246
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_13513)
Rat: Fgf1, HEPARIN-BINDING GROWTH FACTOR 1 PRECURSOR.
Mouse: Fgf1, HEPARIN-BINDING GROWTH FACTOR 1 PRECURSOR.
Mouse: Fgf1, FIBROBLAST GROWTH FACTOR-1 (FRAGMENT).
Mouse: Fgf1, 9 KDA PROTEIN.
Human: FGF1, HEPARIN-BINDING GROWTH FACTOR 1 PRECURSOR.
Human: FGF1, FIBROBLAST GROWTH FACTOR 1 (ACIDIC) ISOFORM 2 PRECURSOR.
Human: FGF1, FIBROBLAST GROWTH FACTOR 1 (ACIDIC) ISOFORM 3 PRECURSOR.
Human: FGF1, ACID FIBROBLAST GROWTH FACTOR-LIKE PROTEIN.
Human: FGF1, ACIDIC FIBROBLAST GROWTH FACTOR (FRAGMENT).
Human: FGF1, SIMILAR TO HEPARIN-BINDING GROWTH FACTOR 1 PRECURSOR.

Annotations for FGF1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
proteinaceous extracellular matrixCIEA IDA IEA ISS 
extracellular regionCNR ISS 
extracellular spaceCIEA IDA IEA ISS ISS 
protein bindingFIPI IPI ISS IEA ISS 
heparin bindingFIEA RCA IEA ISS 
growth factor activityFTAS IEA RCA IEA IDA ISS ISS 
fibroblast growth factor receptor bindingFIEA 
regulation of progression through cell cyclePIEA IEA IEA 
protein kinase cascadePIDA 
anatomical structure morphogenesisPTAS ISS 
positive regulation of epithelial cell proliferationPIDA 
positive regulation of cell adhesionPIDA 
lung developmentPIEA IDA IEA ISS 
cell differentiationPIEA IEA IEA 
cell proliferationPIEA RCA IEA ISS 
nervous system developmentPIDA 
signal transductionPNAS IEA ISS 
cell-cell signalingPNR ISS 
induction of an organPIEA IDA IEA ISS 
angiogenesisPIEA RCA IEA ISS 
multicellular organismal developmentPTAS IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (4)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
nervous system phenotypeMPUn
normal phenotypeMPUn
hematopoietic system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
MAPK signaling pathway (04010)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Regulation of actin cytoskeleton (04810)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway