IpiRecord: IPI00012069

IPI00012069 - NQO1, NAD.
Uniprot Accession: Q53G81
Uniprot ID: Q53G81_HUMAN
Mapping: Chr 16, 68300808 - 68318034
Entrez Gene: 1728
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_14102)
Rat: Nqo1, NAD.
Mouse: Nqo1, NAD.
Human: NQO1, NAD.
Human: NQO1, NQO1 PROTEIN (FRAGMENT).
Human: NQO1, NAD(P)H MENADIONE OXIDOREDUCTASE 1, DIOXIN-INDUCIBLE ISOFORM B.

Annotations for NQO1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
cytoplasmCTAS IEA ISS 
cytochrome-b5 reductase activityFTAS ISS 
NAD(P)H dehydrogenase (quinone) activityFTAS IDA IDA IDA ISS ISS IEA 
oxidoreductase activityFIEA IEA IEA IEA 
coenzyme bindingFIEA IEA IEA 
response to toxinPTAS ISS 
positive regulation of neuron apoptosisPIMP 
nitric oxide biosynthetic processPTAS ISS 
xenobiotic metabolic processPTAS ISS 
synaptic transmission, cholinergicPTAS ISS 
response to oxidative stressPIMP IEP ISS IEA 
electron transportPIEA IEA IEA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (6)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn
tumorigenesisMPUn
hematopoietic system phenotypeMPUn
liver/biliary system phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (3)

Compiled Pathway Ontology Annotations (from IPI)

PW Term Aspect Human Mouse Rat
steroid biosynthetic pathwayWIEA
cellular detoxification pathwayWTAS
oxidative stress response pathwaysWTAS

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Biosynthesis of steroids (00100)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway