IpiRecord: IPI00012369

IPI00012369 - MAD2L1, MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A.
Uniprot Accession: Q6IRW7
Uniprot ID: Q6IRW7_HUMAN
Mapping: Chr 4, 121200029 - 121207411
Entrez Gene: 4085
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_4648)
Rat: Mad2l1_predicted, SIMILAR TO MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A.
Mouse: Mad2l1, MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A.
Human: MAD2L1, MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A.
Human: MAD2L1, MAD2 MITOTIC ARREST DEFICIENT-LIKE 1 VARIANT.

Annotations for MAD2L1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
kinetochoreCTAS IDA ISS ISS 
spindle pole bodyCIDA ISS 
nucleusCIEA IEA 
chromosome, pericentric regionCIDA ISS 
protein bindingFIPI IPI ISS 
molecular_functionFND 
cell divisionPIEA IEA 
mitosisPTAS IEA IEA IEA ISS 
negative regulation of mitotic metaphase/anaphase transitionPTAS ISS 
mitotic cell cycle spindle assembly checkpointPIMP ISS ISS 
cell cyclePIEA IEA 
mitotic cell cycle checkpointPTAS ISS 
mitotic sister chromatid segregationPIMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
cellular phenotypeMPUn
immune system phenotypeMPUn
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
tumorigenesisMPUn
hematopoietic system phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (1)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Cell cycle (04110)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway