IpiRecord: IPI00012760

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
extracellular space	C	ISS	IDA	ISS ISS IDA
extracellular region	C	IEA	IEA	IEA
growth factor activity	F	IEA	IDA	ISS IEA
cytokine activity	F			TAS
protein binding	F	IEA	IPI	ISS IEA
hormone activity	F	IEA	IEA	IEA
negative regulation of metabolic process	P			IDA
bile acid metabolic process	P	IEA	IDA	ISS IEA
intracellular signaling cascade	P			TAS IDA
adult feeding behavior	P	ISS	IDA	ISS
JAK-STAT cascade	P			TAS
regulation of metabolic process	P	IEA	IMP	ISS
cAMP-mediated signaling	P			TAS
cholesterol metabolic process	P		IGI
fatty acid catabolic process	P			IDA
lipid metabolic process	P	IEA	IMP	ISS IEA
glucose metabolic process	P	IEA	IMP	ISS IEA
ovulation from ovarian follicle	P			IDA
cell-cell signaling	P	NR		ISS
energy reserve metabolic process	P	TAS		IDA ISS
eating behavior	P	IEA	IGI	ISS IEA
negative regulation of appetite	P	ISS	IDA	ISS
regulation of cholesterol absorption	P	IEA	IDA	ISS IEA
signal transduction	P	IEA	IEA	IEA
positive regulation of myeloid cell differentiation	P	IEA	IDA	ISS IEA

Cellular Component

Biological Process

Molecular Function

Phenotype (15)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
cellular phenotype	MP		Un
adipose tissue phenotype	MP		Un
behavior/neurological phenotype	MP		Un
endocrine/exocrine gland phenotype	MP		Un
homeostasis/metabolism phenotype	MP		Un Un
immune system phenotype	MP		Un
skeleton phenotype	MP		Un Un
muscle phenotype	MP		Un
renal/urinary system phenotype	MP		Un
cardiovascular system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un
reproductive system phenotype	MP		Un
hematopoietic system phenotype	MP		Un Un
growth/size phenotype	MP		Un Un
liver/biliary system phenotype	MP		Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (4)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
altered leptin system pathway	W			TAS
leptin system pathway	W			TASISS
energy homeostasis pathway	W			IDA
altered energy homeostasis pathway	W			TAS

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Neuroactive ligand-receptor interaction (04080)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Cytokine-cytokine receptor interaction (04060)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway