IpiRecord: IPI00012835

IPI00012835 - CTBP1, C-TERMINAL-BINDING PROTEIN 1.
Uniprot Accession: Q4W5N3
Uniprot ID: Q4W5N3_HUMAN
Mapping: Chr 4, 1195228 - 1232925
Entrez Gene: 1487
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_11923)
Rat: Ctbp1, C-TERMINAL-BINDING PROTEIN 1.
Mouse: Ctbp1, ISOFORM 1 OF C-TERMINAL-BINDING PROTEIN 1.
Mouse: Ctbp1, ISOFORM 2 OF C-TERMINAL-BINDING PROTEIN 1.
Mouse: Ctbp1, ISOFORM 3 OF C-TERMINAL-BINDING PROTEIN 1.
Rat: Ctbp1, C-TERMINAL BINDING PROTEIN 1.
Human: CTBP1, C-TERMINAL-BINDING PROTEIN 1.
Human: CTBP1, CTBP1 PROTEIN.
Human: CTBP1, C-TERMINAL BINDING PROTEIN 1 ISOFORM 2.

Annotations for CTBP1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
nucleusCIEA IEA IEA 
Golgi apparatusCIEA IEA 
cytoplasmCIEA IEA 
transcription factor complexCIDA 
cytosolCIDA 
acyltransferase activityFTAS 
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptorFIEA IEA 
protein bindingFIPI IMP ISS 
transcription corepressor activityFTAS 
oxidoreductase activityFIEA IEA IEA 
transcription factor bindingFIPI IPI ISS ISS 
protein C-terminus bindingFTAS ISS 
cofactor bindingFIEA IEA 
NAD bindingFIEA IEA 
transcription factor activityFIDA 
membrane fusionPTAS 
metabolic processPIEA IEA 
protein amino acid phosphorylationPTAS ISS 
negative regulation of cell proliferationPTAS ISS 
negative regulation of transcription from RNA polymerase II promoterPIMP 
viral genome replicationPTAS ISS 
Golgi organization and biogenesisPIMP 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (8)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
embryogenesis phenotypeMPUn
lethality-embryonic/perinatalMPUn
skeleton phenotypeMPUn
lethality-postnatalMPUn
muscle phenotypeMPUn
nervous system phenotypeMPUn
cardiovascular system phenotypeMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (3)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Chronic myeloid leukemia (05220)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Wnt signaling pathway (04310)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Notch signaling pathway (04330)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway