IpiRecord: IPI00012870

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term	Aspect	Human	Mouse	Rat
cytosol	C			IDA
plasma membrane	C			IDA
lamellipodium	C		IDA	ISS
ATP binding	F	IEA	IEA IEA	IEA
protein binding	F	IPI	IPI	ISS ISS IEA
protein serine/threonine kinase activity	F	TAS IEA	IEA IEA	TAS ISS IDA IEA
protein kinase activity	F		IEA
nucleotide binding	F	IEA	IEA	IEA
kinase activity	F		IEA
transferase activity	F	IEA	IEA	IEA
protein modification process	P	TAS
protein amino acid phosphorylation	P	IEA	IEA	TAS IDA IEA
regulation of JNK cascade	P		IDA	ISS

Cellular Component

Biological Process

Molecular Function

Phenotype (16)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term	Aspect	Human	Mouse	Rat
skin/coat/nails phenotype	MP		Un
cellular phenotype	MP		Un
adipose tissue phenotype	MP		Un Un
endocrine/exocrine gland phenotype	MP		Un Un Un
homeostasis/metabolism phenotype	MP		Un Un Un
growth/size phenotype	MP		Un Un
lethality-embryonic/perinatal	MP		Un Un
skeleton phenotype	MP		Un
reproductive system phenotype	MP		Un
nervous system phenotype	MP		Un
respiratory system phenotype	MP		Un
digestive/alimentary phenotype	MP		Un Un
muscle phenotype	MP		Un Un
postnatal growth retardation	N			ISS
increased circulating glucose level	N			ISS
increased circulating insulin level	N			ISS

Disease (1)

Compiled Disease Ontology Annotations (from IPI)

DO Term	Aspect	Human	Mouse	Rat
Insulin Resistance	D			ISS

Pathway (1)

Compiled Pathway Ontology Annotations (from IPI)

PW Term	Aspect	Human	Mouse	Rat
phosphatidylinositol 3 kinase-Akt signaling pathway	W			IMP

KEGG Pathway (17)

KEGG Pathways for this protein (from IPI)

KEGG Pathway	Human	Mouse	Rat
Glioma (05214)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
T cell receptor signaling pathway (04660)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Chronic myeloid leukemia (05220)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
B cell receptor signaling pathway (04662)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
mTOR signaling pathway (04150)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Toll-like receptor signaling pathway (04620)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Adipocytokine signaling pathway (04920)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Fc epsilon RI signaling pathway (04664)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Apoptosis (04210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
MAPK signaling pathway (04010)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Jak-STAT signaling pathway (04630)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
VEGF signaling pathway (04370)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Tight junction (04530)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Colorectal cancer (05210)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Pancreatic cancer (05212)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Insulin signaling pathway (04910)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway
Focal adhesion (04510)	Present in KEGG pathway	Present in KEGG pathway	Present in KEGG pathway