IpiRecord: IPI00012877

IPI00012877 - IFNAR1, INTERFERON-ALPHA/BETA RECEPTOR ALPHA CHAIN PRECURSOR.
Uniprot Accession: Q6PKD7
Uniprot ID: Q6PKD7_HUMAN
Mapping: Chr 21, 33619079 - 33654038
Entrez Gene: 3454
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_10381)
Rat: Ifnar1_predicted, SIMILAR TO INTERFERON-ALPHA/BETA RECEPTOR ALPHA CHAIN PRECURSOR.
Mouse: Ifnar1, INTERFERON-ALPHA/BETA RECEPTOR ALPHA CHAIN PRECURSOR.
Mouse: Ifnar1, INTERFERON ALPHA/BETA RECEPTOR (FRAGMENT).
Human: IFNAR1, INTERFERON-ALPHA/BETA RECEPTOR ALPHA CHAIN PRECURSOR.
Human: IFNAR1, CDNA FLJ41819 FIS, CLONE NT2RI2014733.
Human: IFNAR1, 15 KDA PROTEIN.

Annotations for IFNAR1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
integral to plasma membraneCTAS ISS 
extracellular spaceCRCA ISS 
membraneCIEA IEA 
integral to membraneCRCA ISS 
phosphoribosylamine-glycine ligase activityFIEA 
receptor activityFIEA IEA 
interferon-alpha/beta receptor activityFTAS ISS 
interferon receptor activityFIMP ISS 
cell surface receptor linked signal transductionPTAS ISS 
JAK-STAT cascadePTAS ISS 
response to virusPTAS ISS 
interferon type I biosynthetic processPIEA IMP ISS 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Phenotype (9)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
skin/coat/nails phenotypeMPUn
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un
skeleton phenotypeMPUn
vision/eye phenotypeMPUn
tumorigenesisMPUn
hematopoietic system phenotypeMPUn Un
no phenotypic analysisMPUn
growth/size phenotypeMPUn

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (4)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
Toll-like receptor signaling pathway (04620)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Jak-STAT signaling pathway (04630)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Cytokine-cytokine receptor interaction (04060)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway