IpiRecord: IPI00012888

IPI00012888 - SPNS1, ISOFORM LONG OF LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1.
Uniprot Accession: O43561-1
Uniprot ID: LAT_HUMAN
Mapping: Chr 16, 28893581 - 28909597
Entrez Gene: 83985
Entrez MapView: Geneprod
+All IPI Database Cross References
IPI records in this ortholog cluster (Cluster: MGI_ORTHOLOGY_1252)
Rat: Lat, LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1.
Mouse: Lat, LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1.
Human: SPNS1, ISOFORM LONG OF LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1.
Human: SPNS1, ISOFORM SHORT OF LINKER FOR ACTIVATION OF T-CELLS FAMILY MEMBER 1.
Human: LAT, TYROSINE ADAPTER PROTEIN) (PP36) (P36-38). ISOFORM SHORT.
Mouse: Spns1, PROTEIN SPINSTER HOMOLOG 1.

Annotations for SPNS1 and orthologs

GO Annotation Table

Compiled GO Annotations (from IPI)

GO Term Aspect Human Mouse Rat
immunological synapseCIDA ISS IEA 
integral to plasma membraneCTAS ISS 
integral to membraneCIEA RCA IEA 
membraneCIEA IEA IEA IEA 
transporter activityFRCA 
receptor signaling protein activityFTAS ISS 
signal transductionPIEA IEA IEA 
transmembrane receptor protein tyrosine kinase signaling pathwayPTAS ISS 
mast cell degranulationPIEA IEA 
cellular defense responsePTAS ISS 
immune responsePIEA IEA 
transportPRCA 

Cellular Component

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Biological Process

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

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Molecular Function

GO Graph Color Key: Rat Mouse Human Rat & Mouse Mouse & Human Rat & Human Rat, Mouse & Human

SVG image

Phenotype (7)

Compiled Mammalian Phenotype Ontology Annotations (from IPI)

MP Term Aspect Human Mouse Rat
homeostasis/metabolism phenotypeMPUn
immune system phenotypeMPUn Un Un Un Un Un
lethality-postnatalMPUn
respiratory system phenotypeMPUn
hematopoietic system phenotypeMPUn Un Un Un
liver/biliary system phenotypeMPUn
life span-post-weaning/agingMPUn Un

Disease (0)

There are no Disease Ontology annotations for this protein in the database

Pathway (0)

There are no Pathway Ontology annotations for this protein in the database

KEGG Pathway (0)

KEGG Pathways for this protein (from IPI)

KEGG Pathway Human Mouse Rat
T cell receptor signaling pathway (04660)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Fc epsilon RI signaling pathway (04664)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway
Natural killer cell mediated cytotoxicity (04650)Present in KEGG pathway Present in KEGG pathwayPresent in KEGG pathway